Larvicidal and structural studies of some triphenyl- and tricyclohexyltin para-substituted benzoates

被引：21
|
作者：
Duong, QY
Song, XQ
Mitrojorgji, E
Gordon, S
Eng, G [1 ]
机构：
[1] Univ Dist Columbia, Dept Chem & Phys, Washington, DC 20008 USA
[2] Walter Reed Army Inst Res, Dept Entomol, Silver Spring, MD 20910 USA
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2006年 / 691卷 / 08期
基金：
美国国家卫生研究院;
关键词：
Aedes aegypti; Anopheles stephensi; aryltins; larvae; mosquito; QSAR; triorganotin para-substituted benzoates;
D O I：
10.1016/j.jorganchem.2005.12.005
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Several new triphenyl- and tricyclohexyltin para-substituted benzoates were synthesized. Their structures were characterized by IR and Mossbauer spectroscopies. The structures were determined to be four-coordinated monomers. Larvicidal activities of the new compounds as well as other benzoates were evaluated against the 2nd larval instar of the Anopheles stephensi and Aedes aegypti mosquitoes. Results from the screening studies indicated that the triphenyltin benzoates were more toxic towards the Ae. aegypti larvae. A quantitative-structure activity relationship was also developed for the Art. stephensi larvae. (c) 2005 Elsevier B.V. All rights reserved.
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页码：1775 / 1779
页数：5
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