Total synthesis, structural revision, and absolute configuration of (+)-clavosolide A

被引:43
|
作者
Son, JB [1 ]
Kim, SN [1 ]
Kim, NY [1 ]
Lee, DH [1 ]
机构
[1] Sogang Univ, Dept Chem, Seoul 121742, South Korea
关键词
D O I
10.1021/ol052851n
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Enantioselective synthesis of 3, a revised structure for clavosolide A, was completed. Both H-1 and C-13 NMR spectra of the natural and synthetic compounds were identical, and optical rotation measurements identified the absolute configuration of the natural clavosolide A as the enantiomer of 3.
引用
收藏
页码:661 / 664
页数:4
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