Novel PET imaging methods for prostate cancer

被引：13

作者：

Mena, Esther ^{[1
]}

Black, Peter C. ^{[2
]}

Rais-Bahrami, Soroush ^{[3
]}

Gorin, Michael ^{[4
]}

Allaf, Mohamad ^{[4
]}

Choyke, Peter ^{[1
]}

机构：

[1] NCI, Mol Imaging Program, 10 Ctr Dr,Bldg 10,Room B3B69F, Bethesda, MD 20892 USA

[2] Univ British Columbia, Vancouver, BC, Canada

[3] Univ Alabama Birmingham, Dept Urol, Birmingham, AL USA

[4] Johns Hopkins Univ, Dept Urol, Baltimore, MD USA

来源：

WORLD JOURNAL OF UROLOGY | 2021年 / 39卷 / 03期

关键词：

Prostate cancer; Molecular imaging; Prostate-specific membrane antigen; Biochemical recurrence; Staging; POSITRON-EMISSION-TOMOGRAPHY; ANDROGEN RECEPTOR EXPRESSION; MEMBRANE ANTIGEN-EXPRESSION; LYMPH-NODE DISSECTION; GA-68-PSMA PET/CT; BIOCHEMICAL RECURRENCE; RADICAL PROSTATECTOMY; SALVAGE RADIOTHERAPY; MULTIPARAMETRIC MRI; C-11-CHOLINE PET/CT;

D O I：

10.1007/s00345-020-03344-3

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction Prostate cancer is a common neoplasm but conventional imaging methods such as CT and bone scan are often insensitive. A new class of PET agents have emerged to diagnose and manage prostate cancer. Methods The relevant literature on PET imaging agents for prostate cancer was reviewed. Results This review shows a broad range of PET imaging agents, the most successful of which is prostate specific membrane antigen (PSMA) PET. Other agents either lack the sensitivity or specificity of PSMA PET. Conclusion Among the available PET agents for prostate cancer, PSMA PET has emerged as the leader. It is likely to have great impact on the diagnosis, staging and management of prostate cancer patients.

引用

页码：687 / 699

页数：13

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