CANADIAN CANCER RISK MANAGEMENT MODEL: EVALUATION OF CANCER CONTROL

被引：24

作者：

Evans, William K. ^{[1
,2
,3
]}

Wolfson, Michael C. ^{[4
]}

Flanagan, William M. ^{[5
,6
]}

Shin, Janey ^{[7
]}

Goffin, John ^{[3
,8
]}

Miller, Anthony B. ^{[9
,10
]}

Asakawa, Keiko ^{[5
,6
]}

Earle, Craig ^{[11
,12
,13
]}

Mittmann, Nicole ^{[14
,15
,16
]}

Fairclough, Lee ^{[17
]}

Oderkirk, Jillian ^{[5
,18
]}

Fines, Philippe ^{[5
]}

Gribble, Stephen ^{[6
]}

Hoch, Jeffrey ^{[19
,20
,21
,22
]}

Hicks, Chantal ^{[6
]}

Omariba, D. Walter R. ^{[23
]}

Ng, Edward ^{[5
]}

机构：

[1] Hamilton Hlth Sci, Juravinski Hosp, Hamilton, ON, Canada

[2] Hamilton Hlth Sci, Ctr Canc, Hamilton, ON, Canada

[3] McMaster Univ, Dept Oncol, Hamilton, ON, Canada

[4] Univ Ottawa, Ottawa, ON, Canada

[5] STAT Canada, Hlth Anal Div, Ottawa, ON, Canada

[6] STAT Canada, Modeling Div, Ottawa, ON, Canada

[7] Canadian Partnership Canc, Analyt & Surveillance, Toronto, ON, Canada

[8] Juravinski Canc Ctr, Hamilton, ON, Canada

[9] Dalla Lana Sch Publ Hlth, Toronto, ON, Canada

[10] Canadian Partnership Canc, Canc Risk Management Initiat, Toronto, ON, Canada

[11] Univ Toronto, Toronto, ON, Canada

[12] Sunnybrook Hlth Sci Ctr, Canc Care Ontario, Toronto, ON M4N 3M5, Canada

[13] Sunnybrook Hlth Sci Ctr, Ontario Inst Canc Res, Inst Clin Evaluat Sci, Toronto, ON M4N 3M5, Canada

[14] Sunnybrook Hlth Sci Ctr, Hlth Outcomes & PharmacoEcon HOPE Res Ctr, Sunnybrook Res Inst, Toronto, ON M4N 3M5, Canada

[15] Univ Toronto, Dept Pharmacol, Toronto, ON, Canada

[16] Western Univ, Richard Ivey Sch Business, Int Ctr Hlth Innovat, London, ON, Canada

[17] Canadian Partnership Canc, Toronto, ON, Canada

[18] Hlth Div Org Econ Cooperat & Dev, Paris, France

[19] Canc Care Ontario, Pharmacoecon Res Unit, Toronto, ON, Canada

[20] St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON M5B 1W8, Canada

[21] Canadian Ctr Appl Res Canc Control ARCC, Toronto, ON, Canada

[22] Univ Toronto, Inst Hlth Policy Management & Evaluat, Toronto, ON, Canada

[23] STAT Canada, Hlth Anal & Modeling Div, Ottawa, ON, Canada

来源：

INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE | 2013年 / 29卷 / 02期

关键词：

Cancer; Simulation model; Policy tool; CELL LUNG-CANCER; CROSS-RESISTANT CHEMOTHERAPY; MULTICENTER RANDOMIZED TRIAL; COLORECTAL-CANCER; BREAST-CANCER; PROLONG SURVIVAL; CARCINOMA; MORTALITY; THERAPY; COSTS;

D O I：

10.1017/S0266462313000044

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Objectives: The aim of this study was to develop a decision support tool to assess the potential benefits and costs of new healthcare interventions. Methods: The Canadian Partnership Against Cancer (CPAC) commissioned the development of a Cancer Risk Management Model (CRMM)-a computer microsimulation model that simulates individual lives one at a time, from birth to death, taking account of Canadian demographic and labor force characteristics, risk factor exposures, and health histories. Information from all the simulated lives is combined to produce aggregate measures of health outcomes for the population or for particular subpopulations. Results: The CRMM can project the population health and economic impacts of cancer control programs in Canada and the impacts of major risk factors, cancer prevention, and screening programs and new cancer treatments on population health and costs to the healthcare system. It estimates both the direct costs of medical care, as well as lost earnings and impacts on tax revenues. The lung and colorectal modules are available through the CPAC Web site (www.cancerview.ca/cancerrriskmanagement) to registered users where structured scenarios can be explored for their projected impacts. Advanced users will be able to specify new scenarios or change existing modules by varying input parameters or by accessing open source code. Model development is now being extended to cervical and breast cancers.

引用

页码：131 / 139

页数：9

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