Tumour Seeding in the Tract of Percutaneous Renal Tumour Biopsy: A Report on Seven Cases from a UK Tertiary Referral Centre

被引:46
|
作者
Macklin, Philip S. [1 ]
Sullivan, Mark E. [2 ]
Tapping, Charles R. [3 ]
Cranston, David W. [2 ]
Webster, Guy M. [2 ]
Roberts, Ian S. D. [1 ]
Verrill, Clare L. [1 ,4 ,5 ]
Browning, Lisa [1 ,5 ]
机构
[1] John Radcliffe Hosp, Dept Cellular Pathol, Headley Way, Oxford OX3 9DU, England
[2] Churchill Hosp, Dept Urol, Oxford, England
[3] John Radcliffe Hosp, Dept Radiol, Oxford, England
[4] Univ Oxford, Nuffield Dept Surg Sci, Oxford, England
[5] Oxford Biomed Res Ctr, Natl Inst Hlth Res, Oxford, England
关键词
Renal; Tumour; Carcinoma; Biopsy; Seeding; FINE-NEEDLE-ASPIRATION; CELL CARCINOMA; PSEUDOCAPSULE;
D O I
10.1016/j.eururo.2018.12.011
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The role of percutaneous renal tumour biopsy (RTB) in the management of radiological indeterminate renal masses is long established. Patients with small renal masses who have biopsy-proven renal cell carcinoma (RCC) may be offered surgery, ablative therapy, or active surveillance, and RTB can provide diagnostic tissue from patients with metastatic disease who might benefit from systemic therapy. Current guidelines suggest that tumour seeding along the needle tract is anecdotal, but several cases have been reported recently, although some have been associated with lack of a coaxial sheath. We report on seven patients who underwent surgical resection of RCC in our tertiary referral institution following diagnostic RTB between 2014 and 2017 for whom RTB tract seeding by tumour was identified on histological examination of the resection specimen. One of these patients subsequently developed local tumour recurrence at the site of the previous biopsy. (C) 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:861 / 867
页数:7
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