The Effects of Resveratrol in the Treatment of Metabolic Syndrome

被引：110

作者：

Hou, Chih-Yao ^{[1
]}

Tain, You-Lin ^{[2
,3
,4
]}

Yu, Hong-Ren ^{[2
,3
,4
]}

Huang, Li-Tung ^{[2
,3
,5
]}

机构：

[1] Natl Kaohsiung Univ Sci & Technol, Dept Seafood Sci, Kaohsiung 811, Taiwan

[2] Kaohsiung Chang Gung Mem Hosp, Inst Translat Res Biomed, Kaohsiung 833, Taiwan

[3] Chang Gung Univ, Coll Med, Kaohsiung 833, Taiwan

[4] Kaohsiung Chang Gung Mem Hosp, Dept Pediat, Kaohsiung 833, Taiwan

[5] Chang Gung Univ, Dept Tradit Med, Linkow 333, Taiwan

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2019年 / 20卷 / 03期

关键词：

resveratrol; metabolic syndrome; high-fat diet; resveratrol derivatives; HIGH-FAT DIET; INSULIN-RESISTANCE; OXIDATIVE STRESS; INDUCED HYPERTENSION; COGNITIVE FUNCTION; GUT MICROBIOTA; ADIPOSE-TISSUE; SWINE MODEL; PREVENTS; DISEASE;

D O I：

10.3390/ijms20030535

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Resveratrol, also known as 3,5,4-trihydroxystilbene, is a natural polyphenol that occurs as a phytoalexin. It is produced by plant sources such as grapes, apples, blueberries, plums, peanuts, and other oilseeds. This compound has a variety of effects on human health and diseases. This review summarizes the mounting evidence that resveratrol is helpful in treating metabolic syndrome and related disorders. Resveratrol can be provided either early as a reprogramming agent or later as part of treatment. A few of the main mechanisms underlying the beneficial effects of resveratrol on metabolic syndrome are outlined. This review also discusses the potential of resveratrol derivatives as a complementary or alternative medicine. In conclusion, resveratrol could be a useful regimen for the prevention and treatment of metabolic syndrome and its related conditions.

引用

页数：15

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