Review on biomedical and bioengineering applications of cellulose sulfate

被引：49

作者：

Zhang, Qilei ^{[1
]}

Lin, Dongqiang ^{[1
]}

Yao, Shanjing ^{[1
]}

机构：

[1] Zhejiang Univ, Coll Chem & Biol Engn, Key Lab Biomass Chem Engn, Minist Educ, Hangzhou 310027, Zhejiang, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2015年 / 132卷

基金：

中国国家自然科学基金;

关键词：

Cellulose sulfate; Cellulose sulfation; Antiviral; Polyelectrolyte complexes; Cell immobilization; POLYELECTROLYTE COMPLEX MICROCAPSULES; HYDROXYPROPYL-METHYL-CELLULOSE; MOLECULAR-WEIGHT; HYDROXYETHYL CELLULOSE; IONIC LIQUIDS; ANTICOAGULATION ACTIVITY; CARBOXYMETHYL CELLULOSE; IMMOBILIZED CULTIVATION; SUBSTITUTION PATTERN; BACTERIAL CELLULOSE;

D O I：

10.1016/j.carbpol.2015.06.041

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Polysaccharide sulfates are naturally existing chemicals that show important biological activities in living organisms. Cellulose sulfate is a semi-synthesized polysaccharide sulfate with a relatively simple chain structure and unique biological properties and its biological applications have been explored in research and clinical trials. With the advance of cellulose derivatization and characterization, cellulose sulfate molecules with tailored structures have been developed to fulfill individual requirements. This review aims to provide a summary of recent development of cellulose sulfate in biomedical applications. Its synthesis pathways were discussed with structure-property relationship elucidated. The application of cellulose sulfate in drug delivery and microbe/cell immobilization were summarized with emphasis given on its polyelectrolyte complex formation processes. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：311 / 322

页数：12

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