The paper reviews nanoscale science and technology of chiral molecules/macromolecules-under two subtopics-chiral nanotechnology and nano-chiral technology. Chiral nanotechnology discusses the nanotechnology, where molecular chirality plays a role in the properties of materials, including molecular switches, molecular motors, and other molecular devices; chiral supramolecules and self-assernbled nanotubes and their functions are also highlighted. Nano-chiral technology describes the nanoscale approaches to chiral technology such as asymmetric synthesis and catalysis, chiral separation and detection, and enantiomeric analysis. Chiral sensors have also been included. The state-of-the-art chiral research at DMSRDE,Kanpur is also presented.