Azithromycin as an alternative to nalidixic acid in the therapy of childhood shigellosis

被引:8
|
作者
Miron, D [1 ]
Torem, M
Merom, R
Colodner, R
机构
[1] HaEmek Med Ctr, Pediat Dept A, Afula, Israel
[2] HaEmek Med Ctr, Microbiol Lab, Afula, Israel
[3] Rappaport Sch Med, Haifa, Israel
关键词
Azithromycin; nalidixic acid; Shigella; child;
D O I
10.1097/00006454-200404000-00022
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In an outbreak of shigellosis in a kibbutz in Northeastern Israel, oral nalidixic acid failed clinically in 35% and microbiologically in 28.4% of 14 children as compared with no clinical and microbiologic failure in 25 children who were treated with oral azithromycin (P < 0.01 and 0.012, respectively). Thus azithromycin could be a suitable alternative to nalidixic acid.
引用
收藏
页码:367 / 368
页数:2
相关论文
共 50 条
  • [21] Randomized comparison of azithromycin versus cefixime for treatment of shigellosis in cheldren
    Basualdo, W
    Arbo, A
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2003, 22 (04) : 374 - 377
  • [22] Randomized controlled comparison of ofloxacin, azithromycin, and an ofloxacin-azithromycin combination for treatment of multidrug-resistant and nalidixic acid-resistant typhoid fever
    Parry, Christopher M.
    Ho, Vo Anh
    Phuong, Le Thi
    Bay, Phan Van Be
    Lanh, Mai Ngoc
    Tung, Le Thanh
    Tham, Nguyen Thi Hong
    Wain, John
    Hien, Tran Tinh
    Farrar, Jeremy J.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2007, 51 (03) : 819 - 825
  • [23] ANTIMICROBIAL THERAPY FOR SHIGELLOSIS
    SALAM, MA
    BENNISH, ML
    REVIEWS OF INFECTIOUS DISEASES, 1991, 13 : S332 - S341
  • [24] THE PROGNOSIS OF CONVULSIONS DURING CHILDHOOD SHIGELLOSIS
    ZVULUNOV, A
    LERMAN, M
    ASHKENAZI, S
    WEITZ, R
    NITZAN, M
    DINARI, G
    EUROPEAN JOURNAL OF PEDIATRICS, 1990, 149 (04) : 293 - 294
  • [25] Lethal encephalopathy complicating childhood shigellosis
    Plötz, FB
    Arets, HGM
    Fleer, A
    Gemke, RJBJ
    EUROPEAN JOURNAL OF PEDIATRICS, 1999, 158 (07) : 550 - 552
  • [26] A possible alternative therapy for childhood aggressivity
    Palermo, George B.
    INTERNATIONAL JOURNAL OF OFFENDER THERAPY AND COMPARATIVE CRIMINOLOGY, 2006, 50 (06) : 607 - 608
  • [27] HALLUCINATIONS AS AN INITIAL MANIFESTATION OF CHILDHOOD SHIGELLOSIS
    ASHKENAZI, S
    BELLAH, G
    CLEARY, TG
    JOURNAL OF PEDIATRICS, 1989, 114 (01): : 95 - 96
  • [28] Lethal encephalopathy complicating childhood shigellosis
    F. B. Plötz
    H. G. M. Arets
    A. Fleer
    R. J. B. J. Gemke
    European Journal of Pediatrics, 1999, 158 : 550 - 552
  • [29] Azithromycin — an alternative to penicillin?
    J Bagg
    British Dental Journal, 2004, 197 (3) : 138 - 138
  • [30] REACTIONS TO NALIDIXIC ACID
    CAHAL, DA
    BRITISH MEDICAL JOURNAL, 1965, 2 (5461): : 590 - &