Inflammatory Response Attenuation in Patients Undergoing Gasless Laparoscopic Gastrectomy

Background/Aims: It has been a matter of debate whether the advantage of gasless laparoscope setting is obvious when compared with the conventional operation. Thus, we compare the systemic response of proinflammatory markers and the adhesion molecules in serum levels after surgery between these two procedures. Methodology: There were 23 patients in the gasless laparoscopy (GL) group, and 12 patients in the open surgery (OS) group. Results: The created wound length was smaller in the GL group (5.3 +/- 0.3cm vs. 8.9 +/- 0.5cm), the post operative recovery including the visual analog pain score on op day and day 1, flatus day, and hospital stay were also shown less in GL group. The levels of IL-6, IL-8 and ICAM were significantly lower in the GL group. Conclusions: Immune response is less in gasless laparoscopy-assisted gastrectomy (GLAG) when compared with traditional approach, and the difference may have effects on the post operative recovery.