NMR assignment and secondary structure of human growth arrest and DNA damage α protein (Gadd45α)

被引：4

作者：

Sanchez, Ricardo ^{[1
]}

Pantoja-Uceda, David ^{[2
]}

Torres, Daniel ^{[3
]}

Prieto, Jesus ^{[3
]}

Campos-Olivas, Ramon ^{[3
]}

Blanco, Francisco J. ^{[1
]}

机构：

[1] CIC Biogune, Struct Biol Unit, Derio 48160, Spain

[2] CSIC, Inst Quim Fis Rocasolano, Mol Struct & Spect Dept, E-28006 Madrid, Spain

[3] CNIO, Struct & Computat Biol Programme, Madrid 28029, Spain

来源：

BIOMOLECULAR NMR ASSIGNMENTS | 2008年 / 2卷 / 02期

关键词：

Gadd45; DNA damage; Growth arrest; Selective labeling; NMR assignment;

D O I：

10.1007/s12104-008-9105-9

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Gadd45 alpha is a predominantly nuclear protein encoded by a DNA-damage-inducible gene which is transcriptionally regulated by the tumor suppressor p53. The interactions of Gadd45 alpha with several other proteins play a central role in DNA repair, cell cycle control and apoptosis. The NMR assignments of human Gadd45 alpha protein reported here provide the basis for further characterization of these interactions.

引用

页码：139 / 142

页数：4

共 50 条

[41] Growth arrest and DNA damage protein 45b (Gadd45b) protects retinal ganglion cells from injuries
Liu, Bin
Suyeoka, Genn
Papa, Salvatore
Franzoso, Guido
Neufeld, Arthur H.
NEUROBIOLOGY OF DISEASE, 2009, 33 (01) : 104 - 110
[42] Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) α and β messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells
Chen, ZX
Clark, S
Birkeland, M
Sung, CM
Lago, A
Liu, RG
Kirkpatrick, R
Johanson, K
Winkler, JD
Hu, ED
CANCER LETTERS, 2002, 188 (1-2) : 127 - 140
[43] Kainate induces the expression of the DNA damage-inducible gene, GADD45, in the rat brain
Zhu, RL
Graham, SH
Jin, K
Stetler, RA
Simon, RP
Chen, J
NEUROSCIENCE, 1997, 81 (03) : 707 - 720
[44] Hyperosmolality causes growth arrest of murine kidney cells -: Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase
Kültz, D
Madhany, S
Burg, MB
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (22) : 13645 - 13651
[45] Selective up-regulation of the growth arrest DNA damage-inducible gene Gadd45 alpha in sensory and motor neurons after peripheral nerve injury
Befort, K
Karchewski, L
Lanoue, C
Woolf, CJ
EUROPEAN JOURNAL OF NEUROSCIENCE, 2003, 18 (04) : 911 - 922
[46] Zinc Supplementation Inhibits Cell Growth and Increases the DNA Damage-Induced Gene (Gadd45) Expression in Human Bronchial Epithelial Cells in Culture
不详
EXPERIMENTAL BIOLOGY AND MEDICINE, 2008, 233 (02) : VIII - VIII
[47] EXPRESSION OF THE GROWTH ARREST AND DNA DAMAGE PROTEIN GADD45β IS INHIBITED BY HEPATITIS C VIRUS IN FULL-LENGTH HCV ORF TRANSGENIC MICE AND HCV-INFECTED PATIENTS WITH HEPATOCELLULAR CARCINOMA
Higgs, Martin
Lerat, Herve
Pawlotsky, Jean-Michel
HEPATOLOGY, 2009, 50 (04) : 932A - 932A
[48] Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA Demethylation in Major Psychosis
Gavin, David P.
Sharma, Rajiv P.
Chase, Kayla A.
Matrisciano, Francesco
Dong, Erbo
Guidotti, Alessandro
NEUROPSYCHOPHARMACOLOGY, 2012, 37 (02) : 531 - 542
[49] p53-Independent WAF1 and GADD45 induction after DNA damage
He, AW
Cory, JG
MOLECULAR BIOLOGY OF THE CELL, 1996, 7 : 128 - 128
[50] Growth Arrest and DNA-Damage-Inducible, Beta (GADD45b)-Mediated DNA Demethylation in Major Psychosis
David P Gavin
Rajiv P Sharma
Kayla A Chase
Francesco Matrisciano
Erbo Dong
Alessandro Guidotti
Neuropsychopharmacology, 2012, 37 : 531 - 542

← 1 2 3 4 5 →