Spontaneous amphophilic focus in the liver of a young Sprague-Dawley rat

被引：0

作者：

Sato, Hiroko ^{[1
]}

Sakairi, Tetsuya ^{[1
]}

Takagi, Shiro ^{[1
]}

Kitamura, Kazuyuki ^{[1
]}

机构：

[1] Mitsubishi Tanabe Pharma Corp, Div Res, Safety Res Labs, Kisarazu, Chiba 2920818, Japan

来源：

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY | 2013年 / 65卷 / 1-2期

关键词：

Altered hepatocellular foci (AHF); Amphophilic; SD rat; Spontaneous occurrence; DEHYDROEPIANDROSTERONE; ADENOMAS;

D O I：

10.1016/j.etp.2011.05.006

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Altered hepatocellular focus was histopathologically observed in the liver of a 6-week-old Sprague-Dawley rat. The hepatocytes within this lesion had diffusely eosinophilic cytoplasm with scattered basophilia and slightly enlarged nuclei with prominent nucleoli. Based on these cytological characteristics, the lesion of these hepatocytes was classified as an amphophilic focus. This is the first report to describe spontaneous amphophilic focus in a young rat. (C) 2011 Elsevier GmbH. All rights reserved.

引用

页码：35 / 37

页数：3

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