Successful control of an outbreak of colonization by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae sequence type 258 in a neonatal intensive care unit, Italy

被引：45
|
作者：
Giuffre, M. [1 ]
Bonura, C. [1 ]
Geraci, D. M. [1 ,2 ]
Saporito, L. [1 ]
Catalano, R. [1 ,3 ]
Di Noto, S. [1 ,4 ]
Nociforo, F. [1 ,4 ]
Corsello, G. [1 ]
Mammina, C. [1 ]
机构：
[1] Univ Palermo, Dept Sci Hlth Promot & Mother Child Care G DAless, I-90127 Palermo, Italy
[2] Univ Palermo, PhD Sch Food & Human Nutr, I-90127 Palermo, Italy
[3] Univ Palermo, Postgrad Specialty Sch Prevent Med, I-90127 Palermo, Italy
[4] Univ Palermo, Postgrad Specialty Sch Pediat, I-90127 Palermo, Italy
来源：
JOURNAL OF HOSPITAL INFECTION | 2013年 / 85卷 / 03期
关键词：
Colonization; Infection control; KPC-Klebsiella pneumoniae; ST258; Multidrug resistance; Neonatal intensive care unit; SURVEILLANCE; INFECTIONS;
D O I：
10.1016/j.jhin.2013.08.004
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
This article reports an outbreak of colonization by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-Kp) sequence type (ST) 258 in a neonatal intensive care unit (NICU) in Palermo, Italy. KPC-Kp ST258 was detected by an active surveillance culture programme. Between 18th September and 14th November 2012, KPC-Kp was isolated from 10 out of 54 neonates admitted in the outbreak period. No cases of infection were recorded. Male sex was associated with colonization, whereas administration of ampicilline-sulbactam plus gentamicin was protective. Infection control interventions interrupted the spread of KPC-Kp without the need to close the NICU to new admissions. (C) 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：233 / 236
页数：4
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