Since the introduction of the first balloon-based enteroscopic technique in 2001, therapeutic balloon-assisted enteroscopy (BAE) using either the single or double balloon enteroscopy technique (respectively SBE and DBE) has evolved rapidly. Argon plasma coagulation (APC), polypectomy, dilation therapy of strictures, and therapy of the pancreatico- biliary system in patients with surgical altered proximal intestinal anatomy: all have been successfully introduced to treat pathological findings in all segments of the small bowel. The clinical impact of treatment of vascular malformations, strictures caused by chronic inflammation (especially Crohn's disease) and polypectomy therapy (especially in the Peutz-Jeghers syndrome) seems evident. The decrease of, often repeated, surgical therapy after successful therapeutic BAE in the latter 2 patient groups appears to be a big step forward in treatment. The development of newer enteroscopes, specialized equipment and improved sedation of patients adds positively to the clinical management of undergoing therapeutic BAE. The overall complication rate of therapeutic BAE seems acceptable, but is higher compared to therapeutic colonoscopy which needs further attention in future. Copyright (C) 2009 S. Karger AG, Basel
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Keio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Keio Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Nishizawa, Toshihiro
Suzuki, Hidekazu
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Keio Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Suzuki, Hidekazu
Fujimoto, Ai
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Keio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Fujimoto, Ai
Ochiai, Yasutoshi
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Keio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Ochiai, Yasutoshi
Kanai, Takanori
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Keio Univ, Sch Med, Dept Internal Med, Div Gastroenterol & Hepatol, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
Kanai, Takanori
Naohisa, Yahagi
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Keio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, JapanKeio Univ, Sch Med, Ctr Canc, Div Res & Dev Minimally Invas Treatment, Tokyo 1608582, Japan
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Veloso, R.
Pinho, R.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Pinho, R.
Rodrigues, A.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Rodrigues, A.
Pais, T.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Pais, T.
Fernandes, C.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Fernandes, C.
Carvalho, J.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal
Carvalho, J.
Fraga, J.
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Ctr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, PortugalCtr Hosp Vila Nova Gaia, Dept Gastroenterol & Hepatol, P-4434502 Vila Nova De Gaia, Portugal