ECHINOCANDIN AND ETHANOL LOCK THERAPY TREATMENT OF FUNGAL CATHETER INFECTIONS

被引：14

作者：

Pieroni, Kevin P. ^{[1
]}

Nespor, Colleen ^{[2
]}

Poole, Robert L. ^{[2
,3
]}

Kerner, John A., Jr. ^{[1
,2
]}

Berquist, William E. ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Div Gastroenterol Hepatol & Nutr, Dept Pediat, Palo Alto, CA 94304 USA

[2] Childrens Home Pharm, Palo Alto, CA USA

[3] Lucile Packard Childrens Hosp Stanford, Dept Pharm, Palo Alto, CA 94304 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2013年 / 32卷 / 03期

关键词：

ethanol locks; catheter infection; fungal infections; BLOOD-STREAM INFECTIONS; PARENTERAL-NUTRITION PATIENTS; CANDIDA-ALBICANS BIOFILMS; INTESTINAL FAILURE; PEDIATRIC-PATIENTS; ANTIFUNGAL AGENTS; EFFICACY; REDUCE;

D O I：

10.1097/INF.0b013e3182784867

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ethanol lock therapy has been implemented to prevent infections of central venous catheters as well as to treat infections. Fungal catheter-associated blood stream infections are historically more difficult to treat and have required removal of central venous catheters. We report the largest case series to date, successfully treating 5 of 7 fungal catheter-associated blood stream infections with ethanol lock therapy and systemic echinocandin administration.

引用

页码：289 / 291

页数：3

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