Nitrogen-Doped Graphene Aerogel for Simultaneous Detection of Dopamine and Ascorbic Acid in Artificial Cerebrospinal Fluid

被引:13
|
作者
Urbanova, Veronika [1 ]
Kment, Stepan [1 ]
Zboril, Radek [1 ]
机构
[1] Palacky Univ Olomouc, Fac Sci, Reg Ctr Adv Technol & Mat, Dept Phys Chem, Olomouc 78371, Czech Republic
关键词
cerebrospinal fluid; dopamine sensing; personal healthcare; graphene aerogel; nitrogen doping; ELECTROCHEMICAL SENSOR; CARBON; ELECTRODE; FUNCTIONALIZATION; OXIDE;
D O I
10.1149/1945-7111/aba6c3
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
Detection of biological relevant analytes using inexpensive and affordable sensors is of high importance for further development of personalized healthcare. Combining electrochemistry with sensing platforms based on new emerging nanomaterials is of immense interest within the scientific community because such connection could bring amelioration in term of sensitivity and possible miniaturization to traditional sensors. Herein, nitrogen-doped graphene aerogel (N-GA) was utilized for detection of biologically important analytes, dopamine and ascorbic acid. Both analytes revealed good linear relationship between current peaks and concentration with detection limit of 0.06 and 0.08 mu M for dopamine and ascorbic acid, respectively. Moreover, N-GA was also applied for simultaneous detection of dopamine along with ascorbic acid in artificial cerebrospinal fluid. In this case, the limit of detection for dopamine reached value of 0.42 mu M.
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页数:7
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