Serine (threonine) phosphatase(s) acting on cAMP-dependent phosphoproteins in mammalian mitochondria

被引：42
|
作者：
Signorile, A [1 ]
Sardanelli, AM [1 ]
Nuzzi, R [1 ]
Papa, S [1 ]
机构：
[1] Univ Bari, Dept Med Biochem & Biol, I-70125 Bari, Italy
来源：
FEBS LETTERS | 2002年 / 512卷 / 1-3期
关键词：
mitochondrial phosphatase; cAMP-dependent protein phosphorylation; mitochondrion; complex I;
D O I：
10.1016/S0014-5793(02)02226-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Immunochemical and functional evidence showing the existence in the inner membrane and matrix fraction of mammalian mitochondria of serine/threonine phosphatases acting on cAMP-dependent phosphoproteins is presented. Mg2+- dependent Ca2+-inhibitable PP2C phosphatase, associated to the inner membrane, dephosphorylates the 18 kDa (NDUFS4 gene) of complex I. (C) 2002 Published by Elsevier Science B.V. on behalf of the Federation of European Biochemical Societies.
引用
收藏
页码：91 / 94
页数：4
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