Human papillomavirus (HPV) infection and genotype frequency in the oral mucosa of newborns in Milan, Italy

被引：10
|
作者：
Martinelli, M. [1 ]
Zappa, A. [1 ]
Bianchi, S. [1 ]
Frati, E. [1 ]
Colzani, D. [1 ]
Amendola, A. [1 ,2 ]
Tanzi, E. [1 ,2 ]
机构：
[1] Univ Milan, Dipartimento Sanita Pubbl Microbiol Virol, I-20133 Milan, Italy
[2] Univ Genoa, Dept Hlth Sci, CIRI IV, Genoa, Italy
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2012年 / 18卷 / 06期
关键词：
Cutaneous HPV; human papillomavirus; mucosal HPV; newborn infections; oral HPV; CHILDREN; TRANSMISSION; COMMON;
D O I：
10.1111/j.1469-0691.2012.03839.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Clin Microbiol Infect 2012; 18: E197E199 Abstract Human papillomavirus (HPV) causes cutaneous and mucosal infections in both adults and children. In order to evaluate HPV prevalence and the spectrum of genotypes in the oral cavity of paediatric subjects, a retrospective study was carried out on oral-pharyngeal swabs collected from 177 newborns aged 06 months. HPV-DNA was detected by a nested-PCR; the viral typing was made through DNA sequencing. HPV infection was identified in 25 subjects (14.1%) and the sequence analysis showed eight distinct genotypes. These data confirm HPV detection in newborn oral mucosa. Further investigations are needed to clarify the methods of HPV acquisition.
引用
收藏
页码：E197 / E199
页数：3
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