Lewis Acids Promoted Formal Intramolecular [3+2] Parallel and Cross-Cycloadditions of Cyclopropane 1,1-Diesters with Allenes

被引：37
|
作者：
Wang, Zhenjun
Ren, Jun
Wang, Zhongwen [1 ]
机构：
[1] Nankai Univ, Synerget Innovat Ctr Chem Sci & Engn Tianjin, State Key Lab, Tianjin 300071, Peoples R China
来源：
ORGANIC LETTERS | 2013年 / 15卷 / 22期
关键词：
RING-SYSTEMS; SUBSTITUTED CYCLOPROPYL; CONSTRUCTION; REACTIVITIES; CARBONYLS; EFFICIENT; CYCLIZATIONS; DERIVATIVES; SELECTIVITY; CHEMISTRY;
D O I：
10.1021/ol402662j
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel Lewis acid promoted formal intramolecular [3 + 2] parallel/cross-cycloaddition of cyclopropane 1,1-diesters with allenes has been successfully developed, in which the two C=C of allenes were involved respectively. This provides a general and efficient strategy for the construction of structurally diverse [4.3.0]nonane and [3.2.1]octane skeletons.
引用
收藏
页码：5682 / 5685
页数：4
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