Anti-GD2 CAR T cells could prove transformative for H3-K27M+ diffuse midline gliomas

被引：2
|
作者：
Furukawa, Koichi [1 ]
Ohmi, Yuhsuke [2 ]
Furukawa, Keiko [1 ]
机构：
[1] Chubu Univ, Coll Life & Hlth Sci, Dept Biomed Sci, Mtaumoto 1200, Kasugai, Aichi 4878501, Japan
[2] Chubu Univ, Coll Life & Hlth Sci, Dept Clin Engn, Kasugai, Aichi, Japan
来源：
TRANSLATIONAL CANCER RESEARCH | 2019年 / 8卷
基金：
日本学术振兴会;
关键词：
ENZYME-MEDIATED ACTIVATION; G(D3) SYNTHASE GENE; LUNG-CANCER; MONOCLONAL-ANTIBODIES; EXPRESSION CLONING; GD2; GANGLIOSIDE; RADICAL SOURCES; STEM-CELLS; GROWTH; PROLIFERATION;
D O I：
10.21037/tcr.2018.08.21
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
[No abstract available]
引用
收藏
页码：S87 / S93
页数：7
相关论文
共 50 条
  • [41] PROBING TCA CYCLE ACTIVITY IN H3WT AND H3K27M-ALTERED DIFFUSE MIDLINE GLIOMAS
    Ijare, Omkar
    Roberson, Jackson
    Kumar, Sushmita
    Ramamurthy, Rishith
    Baskin, David S.
    Pichumani, Kumar
    NEURO-ONCOLOGY, 2023, 25
  • [42] Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant
    de Billy, Emmanuel
    Pellegrino, Marsha
    Orlando, Domenico
    Pericoli, Giulia
    Ferretti, Roberta
    Businaro, Pietro
    Ajmone-Cat, Maria Antonietta
    Rossi, Sabrina
    Petrilli, Lucia Lisa
    Maestro, Nicola
    Diomedi-Camassei, Francesca
    Pezzullo, Marco
    De Stefanis, Cristiano
    Bencivenga, Paola
    Palma, Alessia
    Rota, Rossella
    Del Bufalo, Francesca
    Massimi, Luca
    Weber, Gerrit
    Jones, Chris
    Carai, Andrea
    Caruso, Simona
    De Angelis, Biagio
    Caruana, Ignazio
    Quintarelli, Concetta
    Mastronuzzi, Angela
    Locatelli, Franco
    Vinci, Maria
    NEURO-ONCOLOGY, 2022, 24 (07) : 1150 - 1163
  • [43] CLINICAL AND GENETIC CHARACTERISTICS OF HISTONE H3 K27M-MUTANT DIFFUSE MIDLINE GLIOMAS IN ADULTS
    Schulte, Jessica
    Buerki, Robin
    Lapointe, Sarah
    Molinaro, Annette
    Zhang, Yalan
    Villanueva-Meyer, Javier
    Perry, Arie
    Phillips, Joanna
    Tihan, Tarik
    Bollen, Andrew
    Pekmezci, Melike
    Butowski, Nicholas
    Bush, Nancy Ann Oberheim
    Taylor, Jennie
    Chang, Susan
    Theodosopoulos, Philip
    Aghi, Manish
    Hervey-Jumper, Shawn
    Berger, Mitchel
    Solomon, David
    Clarke, Jennifer
    NEURO-ONCOLOGY, 2020, 22 : 170 - 171
  • [44] Spinal Cord Diffuse Midline Gliomas With H3 K27m-Mutant: Clinicopathological Features and Prognosis
    Wang, Yong-Zhi
    Zhang, Yao-Wu
    Liu, Wei-Hao
    Chai, Rui-Chao
    Cao, Ren
    Wang, Bo
    An, Song-Yuan
    Jiang, Wen-Ju
    Xu, Yu-Lun
    Yang, Jun
    Jia, Wen-Qing
    NEUROSURGERY, 2021, 89 (02) : 300 - 307
  • [45] Characteristics of Adult Diffuse Midline Gliomas, Including a Case with False Negative H3K27M Immunohistochemistry
    El-Sharkawy, Farah
    Wang, Allan
    Kolster, Rachel
    Phillips, Richard
    Chen, H. Isaac
    Bagley, Stephen
    Rosenbaum, Jason
    Nasrallah, MacLean
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2021, 80 (06): : 571 - 571
  • [46] Diffuse midline gliomas with H3F3B K27I mutation: not all H3 K27M-negative gliomas are histone H3 wildtype
    Lee, Julieann
    Cadwell, Cathryn
    Sloan, Emily
    Hwang, Dick
    Phillips, Joanna
    Pekmezci, Melike
    Bollen, Andrew
    Tihan, Tarik
    Perry, Arie
    Solomon, David
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 2020, 79 (06): : 672 - 672
  • [47] Antibody-drug conjugates for H3K27M-mutant diffuse midline gliomas: prospects and challenges
    Rechberger, Julian S.
    Power, A. Erica
    Millesi, Elena
    Daniels, David J.
    THERAPEUTIC DELIVERY, 2021, 12 (08)
  • [48] Diffusion and perfusion imaging biomarkers of H3 K27M mutation status in diffuse midline gliomas
    Kathrani, Nihar
    Chauhan, Richa Singh
    Kotwal, Abhishek
    Kulanthaivelu, Karthik
    Bhat, Maya Dattatraya
    Saini, Jitender
    Prasad, Chandrajit
    Chakrabarti, Dhritiman
    Santosh, Vani
    Uppar, Alok Mohan
    Srinivas, Dwarakanath
    NEURORADIOLOGY, 2022, 64 (08) : 1519 - 1528
  • [49] The emerging role of nanotechnology in pursuit of successful drug delivery to H3K27M diffuse midline gliomas
    A Power, Erica
    Rechberger, Julian S.
    Lu, Victor M.
    Daniels, David J.
    NANOMEDICINE, 2021, 16 (16) : 1343 - 1346
  • [50] Diffusion and perfusion imaging biomarkers of H3 K27M mutation status in diffuse midline gliomas
    Nihar Kathrani
    Richa Singh Chauhan
    Abhishek Kotwal
    Karthik Kulanthaivelu
    Maya Dattatraya Bhat
    Jitender Saini
    Chandrajit Prasad
    Dhritiman Chakrabarti
    Vani Santosh
    Alok Mohan Uppar
    Dwarakanath Srinivas
    Neuroradiology, 2022, 64 : 1519 - 1528
12345