Enantioselective and Diastereoselective Conjugate Radical Additions to -Arylidene Ketones and Lactones

被引：3
|
作者：
Zhao, Changjia [1 ]
Sibi, Mukund P. [1 ]
机构：
[1] North Dakota State Univ, Dept Chem & Biochem, POB 2735, Fargo, ND 58108 USA
来源：
SYNLETT | 2017年 / 28卷 / 20期
关键词：
enantioselective radical reaction; arylidene ketones and lactones; diastereoselectivity; conjugate addition; chiral salen Lewis acid; LEWIS-ACID CATALYSIS; ALPHA-AMINO RADICALS; PHOTOREDOX CATALYSIS; BRONSTED ACID; LIGANDS; ENONES;
D O I：
10.1055/s-0036-1590930
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly stereoselective conjugate radical addition to arylidene ketones and lactones has been developed. The conjugate radical additions using chiral salen Lewis acids proceeds with up to 99:1 dr and 87% ee in good to excellent chemical yields.
引用
收藏
页码：2971 / 2975
页数：5
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