Total synthesis of tanshinone IIA

被引:7
|
作者
Huang, He [1 ]
Song, Chuanjun [1 ]
Wang, Zhen [1 ]
Li, Mengyang [1 ]
Chang, Junbiao [1 ]
机构
[1] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China
关键词
Tanshinone IIA; Total synthesis; Furan; Acyloin; HYDROGEN-PEROXIDE; ACTIVATION; CHEMISTRY; FACILE; INHIBITION; APOPTOSIS; CELLS;
D O I
10.1016/j.tetlet.2020.152102
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel synthetic route toward tanshinone IIA has been developed. Key steps involve a base mediated furan ring formation, and an acyloin condensation reaction to construct the ortho-quinone ring. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页数:4
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