mitochondrial replacement techniques (MRT);
parenthood;
regulation of human reproduction;
reproductive ethics;
mitochondrial donation;
IDENTITY;
CLONING;
D O I:
10.1177/0162243920934542
中图分类号:
D58 [社会生活与社会问题];
C913 [社会生活与社会问题];
学科分类号:
摘要:
Since mitochondrial replacement techniques (MRT) were developed and clinically introduced in the United Kingdom (UK), there has been much discussion of whether these lead to children borne of three parents. In the UK, the regulation of MRT has dealt with this by stipulating that egg donors for the purposes of MRT are not genetic parents even though they contribute mitochondrial DNA (mtDNA) to offspring. In this paper, I examine the way that the Human Fertilisation and Embryology Act in the UK manages the question of parentage. I argue that the Act breaks the link typically made between genetic causation and genetic parenthood by redefining genetic causation solely in terms of nuclear genetics. Along with this, mtDNA is construed as a kind of supplement to the nuclear family. Drawing on the account of the supplement developed by Jacques Derrida, I argue that mtDNA and the women who donate it are seen as both essential to establishing the nuclear family but also exterior to and insignificant for it.
机构:
Univ Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Kopinski, Piotr K.
Janssen, Kevin A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Epigenet Inst, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Janssen, Kevin A.
Schaefer, Patrick M.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Schaefer, Patrick M.
Trefely, Sophie
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Canc Biol, Philadelphia, PA 19104 USA
Drexel Univ, AJ Drexel Autism Inst, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Trefely, Sophie
Perry, Caroline E.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Perry, Caroline E.
Potluri, Prasanth
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Potluri, Prasanth
Tintos-Hernandez, Jesus A.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Tintos-Hernandez, Jesus A.
Singh, Larry N.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Singh, Larry N.
Karch, Kelly R.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Epigenet Inst, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Karch, Kelly R.
Campbell, Sydney L.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Canc Biol, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Campbell, Sydney L.
Doan, Mary T.
论文数: 0引用数: 0
h-index: 0
机构:
Drexel Univ, AJ Drexel Autism Inst, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Doan, Mary T.
Jiang, Helen
论文数: 0引用数: 0
h-index: 0
机构:
Drexel Univ, AJ Drexel Autism Inst, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Jiang, Helen
Nissim, Itzhak
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Nissim, Itzhak
Nakamaru-Ogiso, Eiko
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Nakamaru-Ogiso, Eiko
Wellen, Kathryn E.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Perelman Sch Med, Dept Canc Biol, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Wellen, Kathryn E.
Snyder, Nathaniel W.
论文数: 0引用数: 0
h-index: 0
机构:
Drexel Univ, AJ Drexel Autism Inst, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Snyder, Nathaniel W.
Garcia, Benjamin A.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Penn, Epigenet Inst, Philadelphia, PA 19104 USA
Univ Penn, Perelman Sch Med, Dept Biochem & Biophys, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
Garcia, Benjamin A.
Wallace, Douglas C.
论文数: 0引用数: 0
h-index: 0
机构:
Childrens Hosp Philadelphia, Ctr Mitochondrial & Epigen Med, Philadelphia, PA 19104 USA
Univ Pennsylvania, Childrens Hosp Philadelphia, Perelman Sch Med, Dept Pediat,Div Human Genet, Philadelphia, PA 19104 USAUniv Penn, Howard Hughes Med Inst, Philadelphia, PA 19104 USA
机构:
IVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, Spain
IVI Fdn, Hlth Res Inst La Fe IIS La Fe, Valencia, SpainIVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, Spain
Subira, Jessica
Soriano, Maria Jose
论文数: 0引用数: 0
h-index: 0
机构:
Hlth Res Inst La Fe IIS La Fe, Reprod Med Res Grp, Valencia, SpainIVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, Spain
Soriano, Maria Jose
del Castillo, Luis Miguel
论文数: 0引用数: 0
h-index: 0
机构:
Hlth Res Inst La Fe IIS La Fe, Reprod Med Res Grp, Valencia, Spain
Univ Valencia, Sch Med, Dept Paediat Obstet & Gynaecol, Valencia, SpainIVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, Spain
del Castillo, Luis Miguel
de los Santos, Maria Jose
论文数: 0引用数: 0
h-index: 0
机构:
IVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, SpainIVI RMA Valencia, IVIRMA Global Res Alliance, Plaza Policia Local 3, Valencia 46015, Spain
机构:
Department of Philosophy, University of Waikato, Hamilton
Department of Philosophy, University of Waikato, HamiltonDepartment of Philosophy, University of Waikato, Hamilton