Physical and biological mechanisms of direct plasma interaction with living tissue

被引:587
|
作者
Dobrynin, Danil [2 ]
Fridman, Gregory [1 ]
Friedman, Gary [2 ]
Fridman, Alexander [3 ]
机构
[1] Drexel Univ, Sch Biomed Engn Sci & Hlth Syst, Philadelphia, PA 19104 USA
[2] Drexel Univ, Dept Elect & Comp Engn, Coll Engn, Philadelphia, PA 19104 USA
[3] Drexel Univ, Dept Mech Engn & Mech, Coll Engn, Philadelphia, PA 19104 USA
来源
NEW JOURNAL OF PHYSICS | 2009年 / 11卷
基金
美国国家科学基金会;
关键词
DIELECTRIC BARRIER DISCHARGE; NITRIC-OXIDE; DNA-DAMAGE; CHEMILUMINESCENT REACTION; LIPID-PEROXIDATION; BLOOD-COAGULATION; SPECIAL-ISSUE; STERILIZATION; INACTIVATION; SKIN;
D O I
10.1088/1367-2630/11/11/115020
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Mechanisms of plasma interaction with living tissues and cells can be quite complex, owing to the complexity of both the plasma and the tissue. Thus, unification of all the mechanisms under one umbrella might not be possible. However, the authors are attempting to make first steps in this direction. In this paper, analysis of interaction of floating electrode dielectric barrier discharge (FE-DBD) with living tissues and cells is presented and biological and physical mechanisms are discussed. In physical mechanisms, charged species are identified as the major contributors to the desired effect and a mechanism of this interaction is proposed. Biological mechanisms are also addressed and a hypothesis of plasma selectivity and its effects is offered.
引用
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页数:26
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