Oxidative modification of proteins and blood antioxidant activity of ground squirrels during induced awakening from hibernation

The intensity of oxidative modification of plasma proteins and activity of the antioxidative system of the blood of the ground squirrels during awakening from hibernation is studied. During waking of animals, processes of oxidative modification of proteins in the blood plasma intensify. While the body temperature rises, the antioxidative activity of hydrophylic components of the blood plasma grows essentially, and erythrocyte superoxide dismutase too. Activity of erythrocyte catalase at all stages of waking is definitely higher than in the control. The received results evidence that the high activity of various links of antioxidative blood protection provides stability to oxidative stress during waking of animals from deep sleep.