Serum Macroelement and Microelement Concentrations in Patients with Polycystic Ovary Syndrome: a Cross-Sectional Study

被引:19
|
作者
Li, Muyan [1 ]
Tang, Yuanyuan [2 ]
Lin, Chunlei [1 ]
Huang, Qiaoying [1 ]
Lei, Danqing [1 ]
Hu, Yanling [1 ,3 ,4 ]
机构
[1] Guangxi Med Univ, Expt Ctr Med Sci, Nanning 530000, Guangxi, Peoples R China
[2] Guangxi Med Univ, Affiliated Hosp 1, Guangxi Reprod Med Res Ctr, Nanning, Guangxi, Peoples R China
[3] Guangxi Med Univ, Ctr Genom & Personalized Med, Nanning, Guangxi, Peoples R China
[4] Guangxi Med Univ, Guangxi Coll & Univ Key Lab Biol Mol Med Res, Nanning, Guangxi, Peoples R China
关键词
Copper and zinc; Polycystic ovary syndrome; Acne; Hirsutism; Infertility; OXIDATIVE STRESS; WOMEN; HOMOCYSTEINE; ASSOCIATION; FERRITIN; COPPER; IRON; ZINC;
D O I
10.1007/s12011-016-0782-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Polycystic ovarian syndrome (PCOS) is one of the most common endocrine diseases. However, its pathogenesis is unclear. We aim to explore the potential relationships between serum macroelements/microelements and PCOS. A total of 1137 women were involved in the current study. PCOS was defined according to ESHRE/ASRM, and complete blood samples were collected. Serum macroelements (calcium and magnesium) and microelements (copper, zinc, and iron) were assayed through atomic absorption spectrophotometry. PCOS patients had significantly higher copper concentrations than patients without PCOS (P < 0.001). By contrast, PCOS patients had lower serum calcium levels than patients without PCOS (P < 0.001). No significant differences were observed in the levels of serum zinc, magnesium, and iron between PCOS and non-PCOS patients. PCOS patients with acne had higher magnesium levels than those without acne (P = 0.020), and PCOS patients with hirsutism had lower magnesium levels than those without hirsutism (P = 0.037). High serum copper and low calcium levels may be correlated with PCOS. Magnesium concentrations are correlated with acne and hirsutism in PCOS patients. These results provide clues to explore the mechanism of PCOS and guidance for element treatments in PCOS patients.
引用
收藏
页码:73 / 80
页数:8
相关论文
共 50 条
  • [11] Cardiac Functions and Peripheral Arterial Stiffness in Patients with Polycystic Ovary Syndrome: A Cross-Sectional Study
    Colak, Ayse
    Ozpelit, Mehmet Emre
    Okyay, Recep Emre
    Kumral, Zeynep
    Ozpelit, Ebru
    CYPRUS JOURNAL OF MEDICAL SCIENCES, 2023, 8 (04): : 250 - 256
  • [12] Evaluation of oxidative status in patients with chronic periodontitis and polycystic ovary syndrome: A cross-sectional study
    Saglam, Ebru
    Canakci, Cenk Fatih
    Sebin, Saime Ozbek
    Saruhan, Nesrin
    Ingec, Metin
    Canakci, Humeyra
    Sezer, Ufuk
    JOURNAL OF PERIODONTOLOGY, 2018, 89 (01) : 76 - 84
  • [13] Polycystic Ovary Syndrome and Obesity: A Cross-Sectional Survey of Patients and Obstetricians/Gynecologists
    Gill, Lisa
    Coborn, Jamie E.
    Hoovler, Anthony R.
    Sherif, Katherine
    JOURNAL OF WOMENS HEALTH, 2023, 32 (06) : 723 - 731
  • [14] Is polycystic ovary syndrome a risk factor for depression and anxiety?: a cross-sectional study
    Gunkaya, Osman Samet
    Tekin, Arzu Bilge
    Bestel, Aysegul
    Arslan, Oguz
    Sahin, Fatih
    Taymur, Bilge Dogan
    Tug, Niyazi
    REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2024, 70 (03):
  • [15] Cross-sectional study of the prevalence of polycystic ovary syndrome in rural and urban populations
    Deswal, Ritu
    Nanda, Smiti
    Ghalaut, Veena S.
    Roy, Prasanta S.
    Dang, Amita S.
    INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS, 2019, 146 (03) : 370 - 379
  • [16] Correlation of Vitamin D Levels with Polycystic Ovary Syndrome: A Cross-sectional Study
    Jauhari, Reenoo
    Mathur, Prashant
    Gupta, Vineeta
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2021, 33 (59B) : 41 - 47
  • [17] Environmental exposure to triclosan and polycystic ovary syndrome: a cross-sectional study in China
    Ye, Jiangfeng
    Zhu, Wenting
    Liu, Han
    Mao, Yuchan
    Jin, Fan
    Zhang, Jun
    BMJ OPEN, 2018, 8 (10):
  • [18] Awareness of Polycystic Ovary Syndrome among Schoolgirls and Their Mothers: A Cross-Sectional Study
    Malekzadeh, Farideh
    Mohammadi, Maryam
    Navid, Behnaz
    Moini, Ashraf
    Omani-Samani, Reza
    INTERNATIONAL JOURNAL OF FERTILITY & STERILITY, 2023, 17 (04) : 299 - 305
  • [19] Association of waist circumference, serum ghrelin level and insulin resistance in polycystic ovary syndrome: a cross-sectional study
    Gupta, Madhur
    Bhojane, Chaitanya
    Rode, Sonali
    Salankar, Harsh
    EGYPTIAN PHARMACEUTICAL JOURNAL, 2023, 22 (04) : 551 - 556
  • [20] Association of insulin resistance with polycystic ovary syndrome phenotypes and patients' characteristics: a cross-sectional study in Iran
    Rahmatnezhad, Leili
    Moghaddam-Banaem, Lida
    Behroozi-Lak, Tahereh
    Shiva, Afshin
    Rasouli, Javad
    REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2023, 21 (01)