Inhibition of both c-Met and EGFR signaling shows synergistic antitumor activity in non-small cell lung cancer model

被引:1
|
作者
Tammam, Jennifer G.
Davis, Lenora
Ware, Chris
Reilly, John F.
Deshmukh, Sujal V.
Dinsmore, Christopher
Marshall, Gary
Harrington, Elizabeth A.
Pan, Bo-Sheng
Lutterbach, Bart A.
Majumder, Pradip K.
机构
关键词
D O I
10.1158/1535-7163.TARG-09-C209
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
C209
引用
收藏
页数:2
相关论文
共 50 条
  • [21] Expression of c-Met and HGF in non-small cell lung carcinomas
    I. V. Korobko
    M. V. Zinov’eva
    E. P. Kopantsev
    A. K. Allakhverdiev
    I. B. Zborovskaya
    E. D. Sverdlov
    Molecular Genetics, Microbiology and Virology, 2007, 22 (2) : 59 - 63
  • [22] SYNERGISTIC ANTITUMOR ACTIVITY OF BEVACIZUMAB AND ERLOTINIB IN EGFR-MUTATED NON-SMALL CELL LUNG CANCER XENOGRAFT MODELS
    Moriya, Yoichiro
    Yamamoto, Kaname
    Yanagisawa, Mieko
    Yorozu, Keigo
    Kurasawa, Mitsue
    Furugaki, Koh
    Iwai, Toshiki
    Ishikura, Nobuyuki
    Harada, Naoki
    JOURNAL OF THORACIC ONCOLOGY, 2013, 8 : S768 - S768
  • [23] The Persistent Promise of Combining HGF/MET and EGFR Inhibition in Non-Small Cell Lung Cancer
    Chuang, Jody C.
    Neal, Joel W.
    CANCER, 2017, 123 (15) : 2798 - 2801
  • [24] Development of a SPECT Tracer to Image c-Met Expression in a Xenograft Model of Non-Small Cell Lung Cancer
    Han, Zhaoguo
    Xiao, Yadi
    Wang, Kai
    Yan, Ji
    Xiao, Zunyu
    Fang, Fang
    Jin, Zhongnan
    Liu, Yang
    Sun, Xilin
    Shen, Baozhong
    JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (11) : 1686 - 1691
  • [25] Cigarette smoke enhances oncogene addiction to c-MET and desensitizes EGFR-expressing non-small cell lung cancer to EGFR TKIs
    Tu, Chih-Yen
    Cheng, Fang-Ju
    Chen, Chuan-Mu
    Wang, Shu-Ling
    Hsiao, Yu-Chun
    Chen, Chia-Hung
    Hsia, Te-Chun
    He, Yu-Hao
    Wang, Bo-Wei
    Hsieh, I-Shan
    Yeh, Yi-Lun
    Tang, Chih-Hsin
    Chen, Yun-Ju
    Huang, Wei-Chien
    MOLECULAR ONCOLOGY, 2018, 12 (05) : 705 - 723
  • [26] Attacking EGFR mutant lung cancer by combined EGFR and c-Met inhibition
    Ortiz-Cuaran, Sandra
    Schoettle, Jakob
    Dahmen, Ilona
    Peifer, Martin
    Wieczoreck, Caroline
    Koker, Mirjam
    Ihle, Michaela A.
    Florin, Alexandra
    Pinther, Berit
    Heukamp, Lukas C.
    Ullrich, Roland T.
    Thomas, Roman K.
    CANCER RESEARCH, 2014, 74 (19)
  • [27] The Src Family Kinases mediate EGFR-induced prolonged c-Met phosphorylation in non-small cell lung cancer
    Dulak, Austin
    Siegfried, Jill
    CANCER RESEARCH, 2009, 69
  • [28] EGFR Inhibition in the Treatment of Non-Small Cell Lung Cancer
    Gerber, David E.
    DRUG DEVELOPMENT RESEARCH, 2008, 69 (06) : 359 - 372
  • [29] Detecting C-MET Amplification in Blood and Tumor Tissue of Non-Small Cell Lung Cancer
    Fang, Meiyu
    Xu, Chunwei
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S356 - S356
  • [30] Deoxybouvardin targets EGFR, MET, and AKT signaling to suppress non-small cell lung cancer cells
    Nam, A-Young
    Joo, Sang Hoon
    Khong, Quan T.
    Park, Jisu
    Lee, Na Yeong
    Lee, Seung-On
    Yoon, Goo
    Park, Jin Woo
    Na, Minkyun
    Shim, Jung-Hyun
    SCIENTIFIC REPORTS, 2024, 14 (01):