In-vitro metabolism of triazolam by human liver microsomes: Role of CYP 3A4 and CYP 3A5.

被引：0
|
作者：
Patki, KC [1 ]
Von Moltke, LL [1 ]
Greenblatt, DJ [1 ]
机构：
[1] Tufts Univ, Sch Med, Boston, MA 02111 USA
来源：
CLINICAL PHARMACOLOGY & THERAPEUTICS | 2002年 / 71卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：P95 / P95
页数：1
相关论文
共 50 条
  • [41] Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes
    Ishiguro, N
    Senda, C
    Kishimoto, W
    Sakai, K
    Funae, Y
    Igarashi, T
    XENOBIOTICA, 2000, 30 (01) : 71 - 80
  • [42] Role of CYP3A enzymes in the biotransformation of triazolam in rat liver
    Warrington, JS
    Greenblatt, DJ
    Von Moltke, LL
    XENOBIOTICA, 2004, 34 (05) : 463 - 471
  • [43] Role of CYP2B6 and CYP3A4 in the in vitro N-dechloroethylation of (R)- and (S)-ifosfamide in human liver microsomes
    Granvil, CP
    Madan, A
    Sharkawi, M
    Parkinson, A
    Wainer, IW
    DRUG METABOLISM AND DISPOSITION, 1999, 27 (04) : 533 - 541
  • [44] In vitro metabolism of brucine by human liver microsomes and its interactions with CYP substrates
    Li, Xin
    Wang, Kai
    Wei, Wei
    Liu, Yong-yu
    Gong, Lu
    CHEMICO-BIOLOGICAL INTERACTIONS, 2013, 204 (03) : 140 - 143
  • [45] In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans
    Hirota, N
    Ito, K
    Iwatsubo, T
    Green, CE
    Tyson, CA
    Shimada, N
    Suzuki, H
    Sugiyama, Y
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2001, 22 (02) : 53 - 71
  • [46] Comparison of the substrate kinetics of pig CYP3A29 with pig liver microsomes and human CYP3A4
    Yao, Min
    Dai, Menghong
    Liu, Zhaoying
    Huang, Lingli
    Chen, Dongmei
    Wang, Yulien
    Peng, Dapeng
    Wang, Xu
    Liu, Zhenli
    Yuan, Zonghui
    BIOSCIENCE REPORTS, 2011, 31 (03) : 211 - 220
  • [47] In vitro metabolism of cyclosporine A by human kidney CYP3A5
    Dai, Y
    Iwanaga, K
    Lin, YS
    Hebert, MF
    Davis, CL
    Huang, WL
    Kharasch, ED
    Thummel, KE
    BIOCHEMICAL PHARMACOLOGY, 2004, 68 (09) : 1889 - 1902
  • [48] Effects of deployment-related chemicals on metabolism of estradiol by human liver microsomes, CYP3A4, and CYP1A2
    Usmani, KA
    Rose, RL
    Hodgson, E
    DRUG METABOLISM REVIEWS, 2004, 36 : 156 - 156
  • [49] Utilization of human liver microsomes to explain individual differences in paclitaxel metabolism by CYP2C8 and CYP3A4
    Taniguchi, R
    Kumai, T
    Matsumoto, N
    Watanabe, M
    Kamio, K
    Suzuki, S
    Kobayashi, S
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2005, 97 (01) : 83 - 90
  • [50] Physcion inhibition of CYP2C9, 2D6 and 3A4 in human liver microsomes
    不详
    PHARMACEUTICAL BIOLOGY, 2024, 62 (01) : 270 - 271
12345