Serotype Distribution and Antimicrobial Resistance of Invasive S. pneumoniae among Indian Children before the Introduction of Pneumococcal Conjugate Vaccine

被引：4
|
作者：
Ganaie, Feroze [1 ]
Govindan, Vandana [1 ]
Nagraj, Geetha [1 ]
Ravikumar, K. L. [1 ]
机构：
[1] Hosp & Res Ctr, Kempegowda Inst Med Sci, Dept Microbiol, Cent Res Lab, KR Rd, Bangalore 560004, Karnataka, India
来源：
JOURNAL OF PEDIATRIC INFECTIOUS DISEASES | 2016年 / 11卷 / 04期
关键词：
invasive pneumococcal disease; serotyping; antimicrobial resistance; STREPTOCOCCUS-PNEUMONIAE; ANTIBIOTIC-RESISTANCE; HIGH PREVALENCE; DISEASE; INFECTIONS; SURVEILLANCE; BANGLADESH; CARRIAGE; TRENDS; 19A;
D O I：
10.1055/s-0036-1597650
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
This study was conducted to provide current information on serotype distribution and drug resistance patterns of invasive Streptococcus pneumoniae among children. Sterile site samples from 1,504 children 5 years, who were clinically and radiologically suspected of having invasive pneumococcal infection were evaluated. The leading serotypes causing invasive pneumococcal disease (IPD) were 1, 6B, and 14. High-level penicillin resistance was observed in 11% of isolates belonging to serotypes 6B, 1, and 5. Multidrug resistance was observed in 24% of strains. Our results reveal that PCV-10 and PCV-13 vaccines can protect against 68% and 78% of IPD serotypes, respectively.
引用
下载
收藏
页码：118 / 125
页数：8
相关论文
共 50 条
  • [21] The Effect of 13-Valent Pneumococcal Conjugate Vaccine on the Serotype Distribution and Antibiotic Resistance Profiles in Children With Invasive Pneumococcal Disease
    Gaviria-Agudelo, Claudia L.
    Jordan-Villegas, Alejandro
    Garcia, Carla
    McCracken, George H., Jr.
    JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY, 2017, 6 (03) : 253 - 259
  • [22] Pneumococcal serotype distribution in invasive paediatric disease in Southern Finland before the introduction of vaccine
    Laitinen, Salla
    Vaara, Martti
    Salo, Eeva
    SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2010, 42 (11-12) : 924 - 930
  • [23] Piliation of Invasive Streptococcus pneumoniae Isolates in the Era before Pneumococcal Conjugate Vaccine Introduction in Malawi
    Kulohoma, Benard W.
    Gray, Katherine
    Kamng'ona, Arox
    Cornick, Jennifer
    Bentley, Stephen D.
    Heyderman, Robert S.
    Everett, Dean B.
    CLINICAL AND VACCINE IMMUNOLOGY, 2013, 20 (11) : 1729 - 1735
  • [24] The Serotype Distribution among Healthy Carriers before Vaccination Is Essential for Predicting the Impact of Pneumococcal Conjugate Vaccine on Invasive Disease
    Flasche, Stefan
    de Waroux, Olivier Le Polain
    O'Brien, Katherine L.
    Edmunds, W. John
    PLOS COMPUTATIONAL BIOLOGY, 2015, 11 (04)
  • [25] Serotype distribution of Streptococcus pneumoniae isolated from patients with invasive pneumococcal disease in Brazil before and after ten-pneumococcal conjugate vaccine implementation
    dos Santos, Silvia R.
    Passadore, Lilian F.
    Takagi, Elizabeth H.
    Fujii, Cristiane M.
    Yoshioka, Cristina R. M.
    Gilio, Alfredo E.
    Martinez, Marina B.
    VACCINE, 2013, 31 (51) : 6150 - 6154
  • [26] Regional differences of invasive pneumococcal disease among German federal states in serotype distribution, pneumococcal vaccine coverage and antimicrobial resistance
    Imoehl, M.
    Reinert, R. R.
    van der Linden, M.
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2009, 299 : 99 - 99
  • [27] Regional differences in serotype distribution, pneumococcal vaccine coverage, and antimicrobial resistance of invasive pneumococcal disease among German federal states
    Imoehl, Matthias
    Reinert, Ralf Rene
    van der Linden, Mark
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2010, 300 (04) : 237 - 247
  • [28] Streptococcus pneumoniae serotype distribution in Vojvodina before the introduction of pneumococcal conjugate vaccines into the National Immunization Program
    Petrovic, Vladimir
    Seguljev, Zorica
    Ristic, Mioljub
    Djekic-Malbasa, Jelena
    Radosavljevic, Biljana
    Medic, Deana
    Mihajlovic-Ukropina, Mira
    Hadnadjev, Mirjana
    Gajic, Ina
    Opavski, Natasa
    SRPSKI ARHIV ZA CELOKUPNO LEKARSTVO, 2016, 144 (9-10) : 521 - 526
  • [29] Burden of invasive pneumococcal disease and serotype distribution among Streptococcus pneumoniae isolates in young children in Europe: impact of the 7-valent pneumococcal conjugate vaccine and considerations for future conjugate vaccines
    Isaacman, Daniel J.
    McIntosh, E. David
    Reinert, Ralf R.
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2010, 14 (03) : E197 - E209
  • [30] Changes in Streptococcus pneumoniae serotype distribution in invasive disease and nasopharyngeal carriage after the heptavalent pneumococcal conjugate vaccine introduction in Bogota, Colombia
    Parra, Eliana L.
    De La Hoz, Fernando
    Diaz, Paula L.
    Sanabria, Olga
    Elena Realpe, Maria
    Moreno, Jaime
    VACCINE, 2013, 31 (37) : 4033 - 4038
12345