Morphologic and molecular prognostic markers in prostate cancer

被引：29
|
作者：
Ross, JS [1 ]
Sheehan, CE
Dolen, EM
Kallakury, BVS
机构：
[1] Albany Med Coll, Dept Pathol & Lab Med, Albany, NY 12208 USA
[2] Albany Med Coll, Dept Radiol, Albany, NY 12208 USA
[3] Millennium Pharmaceut Inc, Cambridge, MA USA
[4] Georgetown Univ, Sch Med, Dept Pathol, Georgetown, MD USA
来源：
ADVANCES IN ANATOMIC PATHOLOGY | 2002年 / 9卷 / 02期
关键词：
prostate cancer; biomarker; prognosis; grade; stage; DNA ploidy; cell proliferation; oncogene; cell adhesion; HER-2/neu; apoptosis; proteasome;
D O I：
10.1097/00125480-200203000-00003
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
In this review, a series of traditional morphology-based measurements, relatively well-documented ancillary biomarkers, and emerging molecular assays are evaluated for their relative ability to predict prognosis in prostate cancer. Prognostic factors that have achieved widespread use and are classified as category I by the College of American Pathologists' Solid Tumor Prognostic Factor Consensus Conference are compared with newer tests that are beginning to be used in clinical practice (category II) and emerging molecular-based assays that have yet to be widely validated in the published literature or in clinical trials (category III).
引用
收藏
页码：115 / 128
页数：14
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