Haematopoietic stem cells show their true colours

被引：2
|
作者：
North, Trista E. [1 ]
Goessling, Wolfram [2 ]
机构：
[1] Harvard Med Sch, Harvard Stem Cell Inst, Dept Pathol, Beth Israel Deaconess Med Ctr, CLS 536,3 Blackfan Circle, Boston, MA 02115 USA
[2] Harvard Med Sch, Harvard Stem Cell Inst, Brigham & Womens Hosp, Genet & Gastroenterol Div, NRB 458,77 Ave Louis Pasteur, Boston, MA 02215 USA
来源：
NATURE CELL BIOLOGY | 2017年 / 19卷 / 01期
关键词：
AORTIC ENDOTHELIUM; CLONAL-TRACKING; IN-VIVO; DYNAMICS;
D O I：
10.1038/ncb3459
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Delineating the behaviour of haematopoietic stem cells (HSCs) in vivo has thus far proven challenging. Two studies in zebrafish and mouse models now track HSCs in vivo using fate mapping with multicolour approaches to provide further insights into clonal events that regulate blood development, HSC function and differentiation during homeostasis and stress conditions.
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页码：10 / 12
页数：3
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