Neutral red as a specific light-up fluorescent probe for i-motif DNA

被引:26
|
作者
Xu, Lijun [1 ,2 ]
Wang, Jine [1 ]
Sun, Na [1 ]
Liu, Min [1 ]
Cao, Yi [1 ]
Wang, Zhili [1 ]
Pei, Renjun [1 ]
机构
[1] Chinese Acad Sci, Key Lab Nanobio Interface, Div Nanobiomed, Suzhou Inst Nanotech & Nanobion, Suzhou 215123, Peoples R China
[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China
基金
中国国家自然科学基金;
关键词
G-QUADRUPLEX; LOGIC GATES; MOLECULAR RECOGNITION; HUMAN TELOMERE; RICH STRAND; BINDING; EQUILIBRIUM; STABILITY; PROTEIN; SENSOR;
D O I
10.1039/c6cc07674b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report a specific light-up fluorescent probe for i-motif DNA for the first time. Compared with the previously reported probes, neutral red could selectively interact with an i-motif and show a significant increase in its fluorescence. This feature makes it advantageous for designing label-free fluorescent sensing systems.
引用
收藏
页码:14330 / 14333
页数:4
相关论文
共 50 条
  • [31] Development of a highly sensitive fluorescent light-up probe for G-quadruplexes
    Hu, Ming-Hao
    Chen, Shuo-Bin
    Guo, Rui-Jun
    Ou, Tian-Miao
    Huang, Zhi-Shu
    Tan, Jia-Heng
    ANALYST, 2015, 140 (13) : 4616 - 4625
  • [32] Silver cations fold i-motif at neutral pH
    Day, Henry A.
    Huguin, Camille
    Waller, Zoe A. E.
    CHEMICAL COMMUNICATIONS, 2013, 49 (70) : 7696 - 7698
  • [33] Structure of i-Motif/Duplex Junctions at Neutral pH
    Serrano-Chacon, Israel
    Mir, Bartomeu
    Escaja, Nuria
    Gonzalez, Carlos
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 143 (33) : 12919 - 12923
  • [34] Dibenzopyridoimidazocinnolinium cations: a new family of light-up fluorescent DNA probes
    Bosch, Pedro
    Sucunza, David
    Mendicuti, Francisco
    Domingo, Alberto
    Vaquero, Juan J.
    ORGANIC CHEMISTRY FRONTIERS, 2018, 5 (12): : 1916 - 1927
  • [35] Flexible amine-functionalized triphenylamine derivative as a fluorescent "light-up" probe for G-quadruplex DNA
    Wang, Ming-Qi
    Liu, Shuo
    Tang, Cai-Ping
    Raza, Aun
    Li, Shuo
    Gao, Lie-Xiong
    Sun, Jing
    Guo, Song-Ping
    DYES AND PIGMENTS, 2017, 136 : 78 - 84
  • [36] A fluorescent light-up probe with AIE characteristics for specific mitochondrial imaging to identify differentiating brown adipose cells
    Gao, Meng
    Sim, Choon Kiat
    Leung, Chris Wai Tung
    Hu, Qinglian
    Feng, Guangxue
    Xu, Feng
    Tang, Ben Zhong
    Liu, Bin
    CHEMICAL COMMUNICATIONS, 2014, 50 (61) : 8312 - 8315
  • [37] Enzyme-driven i-motif DNA folding for logic operations and fluorescent biosensing
    Wang, Ming
    Zhang, Guanxin
    Zhang, Deqing
    CHEMICAL COMMUNICATIONS, 2015, 51 (18) : 3812 - 3815
  • [38] Crystal violet as a fluorescent switch-on probe for i-motif: label-free DNA-based logic gate
    Ma, Dik-Lung
    Kwan, Maria Hiu-Tung
    Chan, Daniel Shiu-Hin
    Lee, Paul
    Yang, Hui
    Ma, Victor Pui-Yan
    Bai, Li-Ping
    Jiang, Zhi-Hong
    Leung, Chung-Hang
    ANALYST, 2011, 136 (13) : 2692 - 2696
  • [39] Interactions of Phenanthroline Compounds with i-Motif DNA
    Gao Ning
    Wang Yanbo
    Wei Chunying
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2014, 30 (03) : 495 - 499
  • [40] DNA i-MOTIF Probed by Photoacoustic Calorimetry
    Butcher, David
    Miksovska, Jaroslava
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 64A - 64A