Successful treatment of a case of relapsed acute promyelocytic leukemia with arsenic trioxide

被引：1
|
作者：
Hirayama, Y [1 ]
Koyama, R [1 ]
Nagai, T [1 ]
Ohta, H [1 ]
Kondo, A [1 ]
Ishikawa, K [1 ]
Ishitani, K [1 ]
Matsunaga, T [1 ]
Sakamaki, S [1 ]
Niitsu, Y [1 ]
机构：
[1] Hokkaido Prefectural Sapporo Kitano Hosp, Sapporo, Hokkaido, Japan
来源：
INTERNAL MEDICINE | 2001年 / 40卷 / 11期
关键词：
ATRA; skin erythema; neuralgia;
D O I：
10.2169/internalmedicine.40.1136
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a patient with an initial relapse of acute promyelocytic leukemia (APL) who achieved a second complete remission (CR) after treatment with arsenic trioxide. The patient, a 66-year-old woman diagnosed as having relapsed APL, received arsenic trioxide intravenously at a dose of 10 mg/day. At day 36, the patient achieved a second CR. The side effects were slight neuralgia and mild skin erythematous changes, which improved following cessation of the drug. Although arsenic trioxide may be effective for relapsed APL, it should be used with caution because of various complications.
引用
收藏
页码：1136 / 1139
页数：4
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