A new hexadeca substituted non-aggregating zinc phthalocyanine

被引：36
|
作者：
Atsay, Armagan [1 ]
Gul, Ahmet [1 ]
Kocak, Makbule Burkut [1 ]
机构：
[1] Istanbul Tech Univ, Dept Chem, TR-34469 Istanbul, Turkey
来源：
DYES AND PIGMENTS | 2014年 / 100卷
关键词：
Phthalocyanine; Hexadeca-substituted; Amphiphilic; Protonation; Non-aggregating; Water-soluble; ELECTRON-TRANSFER REDUCTION; PHOTODYNAMIC THERAPY; CANCER-CELLS; DERIVATIVES; DISTORTION; COMPLEXES;
D O I：
10.1016/j.dyepig.2013.09.012
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
In this work, a new hexadeca substituted zinc phthalocyanine 4 bearing hexyloxy groups in non-peripheral positions and 3-(diethylamino)phenoxy groups in peripheral positions and its corresponding water-soluble octacationic derivative 5 have been reported. The new compounds have been characterized by elemental analysis, IR, UV, NMR and mass spectra. Zinc phthalocyanine showed excellent solubility in organic solvents of wide polarity range due to its amphiphilic nature and it enabled us to carry out detailed UV-Vis studies in different solvents. Octacationic zinc phthalocyanine 5 was soluble in DMF, DMSO and water. UV-Vis spectra of 5 in DMSO, DMF and water showed sharp Q band absorption as an indication of monomeric form even in aqueous media. This property of water-soluble non-aggregating zinc phthalocyanine is promising as a photosensitizer in Photodynamic Therapy of Cancer. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码：177 / 183
页数：7
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