Assignment of the gene encoding type 1 gamma protein phosphatase catalytic subunit (PPP1CC) on human, rat, and mouse chromosomes

被引:2
|
作者
Saadat, M
Nomoto, K
Mizuno, Y
Kikuchi, K
Yoshida, MC
机构
[1] HOKKAIDO UNIV,FAC SCI,CHROMOSOME RES UNIT,SAPPORO,HOKKAIDO 060,JAPAN
[2] HOKKAIDO UNIV,INST IMMUNOL SCI,BIOCHEM SECT,SAPPORO,HOKKAIDO 060,JAPAN
[3] HOKKAIDO UNIV,GRAD SCH ENVIRONM EARTH SCI,DIV BIOL SCI,LAB CYTOGENET,SAPPORO,HOKKAIDO 060,JAPAN
来源
JAPANESE JOURNAL OF HUMAN GENETICS | 1996年 / 41卷 / 01期
关键词
protein phosphatase type 1; PP1; gamma; comparative gene mapping; FISH;
D O I
10.1007/BF01892623
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Using fluorescent in situ hybridization (FISH) method, a gene encoding the catalytic subunit of protein phosphatase type 1 gamma (PPP1CC) was mapped to human 12q24.1-q24.2, rat 7q22, and mouse 10C. These results indicate that the PPP1CC is a member of conserved synteny group between rat chromosome 7, mouse chromosome 10 and human chromosome 12. These data and mapping data about other members of PP1 family show that in spite of the high identity of PP1 isoforms, each isoform is encoded by different genes which located on different chromosomes in human, rat, and mouse.
引用
收藏
页码:159 / 165
页数:7
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