Protein-Based Hydrogels for Tissue Engineering

被引：45

作者：

Schloss, Ashley C. ^{[1
]}

Williams, Danielle M. ^{[1
]}

Regan, Lynne J. ^{[1
,2
,3
]}

机构：

[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA

[2] Yale Univ, Dept Chem, New Haven, CT 06520 USA

[3] Yale Univ, Integrated Grad Program Phys & Engn Biol, New Haven, CT 06520 USA

来源：

PROTEIN-BASED ENGINEERED NANOSTRUCTURES | 2016年 / 940卷

关键词：

Hydrogels; Tissue engineering; Protein materials; Smart biomaterials; Self-assembly; Protein engineering; Mechanical properties; Stimuli-responsive materials; Biocompatibility; SPYTAG-SPYCATCHER CHEMISTRY; PEPTIDE HYDROGELS; SMART GELS; DESIGN; SCAFFOLDS; MICROARCHITECTURE; PROLIFERATION; MIGRATION; GROWTH;

D O I：

10.1007/978-3-319-39196-0_8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The tunable mechanical and structural properties of protein-based hydrogels make them excellent scaffolds for tissue engineering and repair. Moreover, using protein-based components provides the option to insert sequences associated with promoting both cellular adhesion to the substrate and overall cell growth. Protein-based hydrogel components are appealing for their structural designability, specific biological functionality, and stimuli-responsiveness. Here we present highlights in the field of protein-based hydrogels for tissue engineering applications including design requirements, components, and gel types.

引用

页码：167 / 177

页数：11

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