Protein-Based Hydrogels for Tissue Engineering

被引：45
|
作者：
Schloss, Ashley C. [1 ]
Williams, Danielle M. [1 ]
Regan, Lynne J. [1 ,2 ,3 ]
机构：
[1] Yale Univ, Dept Mol Biophys & Biochem, New Haven, CT 06520 USA
[2] Yale Univ, Dept Chem, New Haven, CT 06520 USA
[3] Yale Univ, Integrated Grad Program Phys & Engn Biol, New Haven, CT 06520 USA
来源：
PROTEIN-BASED ENGINEERED NANOSTRUCTURES | 2016年 / 940卷
关键词：
Hydrogels; Tissue engineering; Protein materials; Smart biomaterials; Self-assembly; Protein engineering; Mechanical properties; Stimuli-responsive materials; Biocompatibility; SPYTAG-SPYCATCHER CHEMISTRY; PEPTIDE HYDROGELS; SMART GELS; DESIGN; SCAFFOLDS; MICROARCHITECTURE; PROLIFERATION; MIGRATION; GROWTH;
D O I：
10.1007/978-3-319-39196-0_8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The tunable mechanical and structural properties of protein-based hydrogels make them excellent scaffolds for tissue engineering and repair. Moreover, using protein-based components provides the option to insert sequences associated with promoting both cellular adhesion to the substrate and overall cell growth. Protein-based hydrogel components are appealing for their structural designability, specific biological functionality, and stimuli-responsiveness. Here we present highlights in the field of protein-based hydrogels for tissue engineering applications including design requirements, components, and gel types.
引用
收藏
页码：167 / 177
页数：11
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