SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the 5-6 luminal loop and prevents K+ access to the ion site

被引：0

作者：

Vagin, O

Denevich, S

Munson, K

Sachs, G

机构：

[1] Univ Calif Los Angeles, Los Angeles, CA 90073 USA

[2] VAGLAHS, Los Angeles, CA USA

来源：

BIOPHYSICAL JOURNAL | 2002年 / 82卷 / 01期

关键词：

D O I：

暂无

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

1264

引用

页码：261A / 261A

页数：1

共 14 条

[1] SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the M5-6 luminal loop, preventing K+ access to the ion binding domain
Vagin, O
Denevich, S
Munson, K
Sachs, G
[J]. BIOCHEMISTRY, 2002, 41 (42) : 12755 - 12762
[2] Inhibition kinetics of the gastric H,K-ATPase by K-competitive inhibitor SCH28080 as a tool for investigating the luminal ion pathway
Vagin, O
Munson, K
Denevich, S
Sachs, G
[J]. NA,K-ATPASE AND RELATED CATION PUMPS: STRUCTURE, FUNCTION, AND REGULATORY MECHANISMS, 2003, 986 : 111 - 115
[3] The K+-competitive inhibitor SCH28080 provides tertiary structural information on the K transport domain of the H,K ATPase
Munson, KB
Vagin, O
Sachs, G
[J]. BIOPHYSICAL JOURNAL, 2002, 82 (01) : 261A - 261A
[4] Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase
Vagin, O
Munson, K
Lambrecht, N
Karlish, SJD
Sachs, G
[J]. BIOCHEMISTRY, 2001, 40 (25) : 7480 - 7490
[5] Investigation of the SCH28080 binding site in the gastric H,K ATPase.
Lambrecht, N
Munson, KB
Vagin, O
Sachs, G
[J]. GASTROENTEROLOGY, 2000, 118 (04) : A888 - A888
[6] SCH28080 PREVENTS OMEPRAZOLE INHIBITION OF THE GASTRIC H+/K+-ATPASE
HERSEY, SJ
STEINER, L
MENDLEIN, J
RABON, E
SACHS, G
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1988, 956 (01) : 49 - 57
[7] SCH-28080 IS A LUMENALLY ACTING, K+-SITE INHIBITOR OF THE GASTRIC (H+ + K+)-ATPASE
KEELING, DJ
LAING, SM
SENNBILFINGER, J
[J]. BIOCHEMICAL PHARMACOLOGY, 1988, 37 (11) : 2231 - 2236
[8] SCH-28080 IS A MORE SELECTIVE INHIBITOR THAN SCH-32651 AT THE K+ SITE OF GASTRIC K+/H+-ATPASE
BEIL, W
STAAR, U
SEWING, KF
[J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 1987, 139 (03) : 349 - 352
[9] Molecular Modeling of SCH28080 binding to the gastric H,K-ATPase and MgATP interactions with SERCA- and Na,K-ATPases
Munson, K
Vagin, O
Sachs, G
Karlish, S
[J]. NA,K-ATPASE AND RELATED CATION PUMPS: STRUCTURE, FUNCTION, AND REGULATORY MECHANISMS, 2003, 986 : 106 - 110
[10] BINDING OF THE (H+ + K+)-ATPASE INHIBITOR, SCH-28080, TO GASTRIC MEMBRANE PREPARATIONS
KEELING, DJ
[J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 1987, 15 (06) : 1138 - 1139

← 1 2 →