Lymphocyte subset reconstitution in pediatric liver recipients induced with steroid-free rabbit anti-human thymocyte globulin

被引：10
|
作者：
Talukdar, Anjan [1 ,2 ]
AshokKumar, Chethan [1 ,2 ]
Farrar, Jennifer [1 ,2 ]
Wilson, Patrick [1 ,2 ]
Janakiramanan, Arun [1 ,2 ]
Tregaskes, Mary [1 ,2 ]
Sindhi, Rakesh [1 ,2 ]
机构：
[1] Childrens Hosp Pgh, Hillman Ctr Pediat Transplantat, Pediat Transplantat Lab, Pittsburgh, PA USA
[2] Univ Pittsburgh, Pittsburgh, PA USA
来源：
PEDIATRIC TRANSPLANTATION | 2008年 / 12卷 / 07期
关键词：
lymphocyte depleting antibodies; pediatric; liver transplantation; immunosuppression; lymphocyte subsets;
D O I：
10.1111/j.1399-3046.2007.00797.x
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence.
引用
收藏
页码：804 / 808
页数：5
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