Estrogen receptor β polymorphisms are associated with bone mass in women and men:: The Framingham study

被引：59
|
作者：
Shearman, AM
Karasik, D
Gruenthal, KM
Demissie, S
Cupples, LA
Housman, DE
Kiel, DP
机构：
[1] Harvard Univ, Sch Med, Dept Med, Div Aging,HRCA Res & Training Inst, Boston, MA 02131 USA
[2] MIT, Canc Res Ctr, Cambridge, MA 02139 USA
[3] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02215 USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 05期
关键词：
estrogen receptor beta; BMD; association; gene; osteoporosis;
D O I：
10.1359/JBMR.0301258
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
ESR2 is expressed in bone cells, yet few studies have tested its variation for association with BMD, an important determinant of osteoporotic fractures. This was investigated in 723 men and 795 women from the Framingham study. Results show association of variation in this gene with BMD in both women and men.
引用
收藏
页码：773 / 781
页数：9
相关论文
共 50 条
  • [41] EFFECTS OF WEIGHT AND BODY-MASS INDEX ON BONE-MINERAL DENSITY IN MEN AND WOMEN - THE FRAMINGHAM-STUDY
    FELSON, DT
    ZHANG, YQ
    HANNAN, MT
    ANDERSON, JJ
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 1993, 8 (05) : 567 - 573
  • [42] ESTROGEN-RECEPTOR GENOTYPES AND BONE-MINERAL DENSITY IN WOMEN AND MEN
    OI, C
    MORRISON, NA
    NGUYEN, TV
    WHITE, CP
    KELLY, PJ
    SAMBROOK, PN
    EISMAN, JA
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 1995, 10 : S170 - S170
  • [43] Central obesity is associated with bone mass: A survey on men and women
    Bekheirnia, MR
    Soltani, A
    Hossein-nezad, A
    Hamidi, Z
    Larijani, B
    [J]. OSTEOPOROSIS INTERNATIONAL, 2004, 15 : S44 - S45
  • [44] Estrogen receptor alpha gene polymorphisms are associated with estradiol levels in postmenopausal women
    Schuit, SCE
    de Jong, FH
    Stolk, L
    Kock, WNH
    van Meurs, JBJ
    Schoofs, MWCJ
    Zillikens, MC
    Hofman, A
    van Leeuwen, JPTM
    Pols, HAP
    Uitterlinden, AG
    [J]. EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2005, 153 (02) : 327 - 334
  • [45] The effects of vitamin D receptor polymorphisms on bone mineral density in men and women
    Whitt, Karen J.
    Ling, Shari M.
    Bos, Angelo J. G.
    Muller, Denis C.
    Roth, Stephen M.
    Ferruccil, Luigi
    [J]. FASEB JOURNAL, 2007, 21 (05): : A174 - A174
  • [46] Association study of estrogen receptor alpha gene polymorphisms with bone mass assessed by quantitative ultrasound in young adults
    María Correa-Rodriguez
    Jacqueline Schmidt-RioValle
    Blanca Rueda-Medina
    [J]. Rheumatology International, 2017, 37 : 1281 - 1286
  • [47] Association study of estrogen receptor alpha gene polymorphisms with bone mass assessed by quantitative ultrasound in young adults
    Correa-Rodriguez, Maria
    Schmidt-RioValle, Jacqueline
    Rueda-Medina, Blanca
    [J]. RHEUMATOLOGY INTERNATIONAL, 2017, 37 (08) : 1281 - 1286
  • [48] Association between estrogen receptor α polymorphisms and equol production, and its relation to bone mass
    Katsuyama, Hironobu
    Arii, Masayuki
    Tomita, Masafumi
    Hidaka, Kazuo
    Watanabe, Yoko
    Tamechika, Yoshie
    Okuyama, Toshiko
    Fushimi, Shigeko
    Maeda, Noriko
    Higashimura, Tsutomu
    Fukunaga, Masao
    Saijoh, Kiyofumi
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2009, 23 (06) : 793 - 798
  • [49] Bone Mass and the Risk of Colon Cancer among Postmenopausal Women The Framingham Study
    Zhang, Yuqing
    Felson, David T.
    Ellison, R. Curtis
    Kreger, Bernard E.
    Schatzkin, Arthur
    Dorgan, Joanne F.
    Cupples, L. Adrienne
    Levy, Daniel
    Kiel, Douglas P.
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2001, 153 (01) : 31 - 37
  • [50] Estrogen receptor alpha gene polymorphisms are associated with changes in bone remodeling markers and treatment response to estrogen
    Rapuri, PB
    Gallagher, JC
    Knezetic, JA
    Haynatzka, V
    [J]. MATURITAS, 2006, 53 (04) : 371 - 379
12345