Estrogen receptor β polymorphisms are associated with bone mass in women and men:: The Framingham study

被引：59
|
作者：
Shearman, AM
Karasik, D
Gruenthal, KM
Demissie, S
Cupples, LA
Housman, DE
Kiel, DP
机构：
[1] Harvard Univ, Sch Med, Dept Med, Div Aging,HRCA Res & Training Inst, Boston, MA 02131 USA
[2] MIT, Canc Res Ctr, Cambridge, MA 02139 USA
[3] Boston Univ, Sch Publ Hlth, Dept Biostat, Boston, MA 02215 USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 05期
关键词：
estrogen receptor beta; BMD; association; gene; osteoporosis;
D O I：
10.1359/JBMR.0301258
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
ESR2 is expressed in bone cells, yet few studies have tested its variation for association with BMD, an important determinant of osteoporotic fractures. This was investigated in 723 men and 795 women from the Framingham study. Results show association of variation in this gene with BMD in both women and men.
引用
收藏
页码：773 / 781
页数：9
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