Hepatitis B virus DNA in blood samples positive for antibodies to core antigen and negative for surface antigen

被引:0
|
作者
Gutiérrez, C
León, G
Loureiro, CL
Uzcátegui, N
Liprandi, F
Pujol, FH
机构
[1] Inst Venezolano Invest Cient, Ctr Microbiol & Biol Celular, Lab Biol Virus, Caracas 1020A, Venezuela
[2] Banco Municipal Sangre, Caracas, Venezuela
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Anti-hepatitis B core antigen (HBcAg)-positive hepatitis B surface antigen (HBsAg)-negative plasma samples from blood donors were tested by nested PCR. DNA positivity was more significantly associated with high levels of anti-HBcAg than with low levels of anti-HBsAg antibodies. Analysis of a dilution of anti-HBcAg antibodies might result in a more rational exclusion of anti-HBcAg-positive HBsAg-negative samples, reducing the number of donations discarded and enabling more countries to incorporate anti-HBcAg testing.
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页码:768 / 770
页数:3
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