The Applications literature associated with nanoscience and nanotechnology research was examined. About 65,000 nanotechnology records for 2005 were retrieved from the Science Citation Index/Social Science Citation Index (SCI/SSCI) (SCI ( 2006). Certain data included herein are derived from the Science Citation Index/Social Science Citation Index prepared by the Thomson Scientific (R), Inc. (Thomson (R)), Philadelphia, Pennsylvania, USA) Through visual inspection of the Abstract phrases, all the diverse non-medical Applications were identified, and the relationships among the Applications, both direct and indirect, were obtained. The medical applications were identified through a fuzzy clustering process. Metrics associated with research literatures for specific Applications/ Applications groups were generated.