Infective endocarditis and meningitis due to Scedosporium prolificans in a renal transplant recipient

被引：22
|
作者：
Uno, Kenji [1 ]
Kasahara, Kei [1 ]
Kutsuna, Satoshi [1 ]
Katanami, Yuichi [1 ]
Yamamoto, Yoshifumi [2 ]
Maeda, Koichi [1 ]
Konishi, Mitsuru [1 ]
Ogawa, Taku [1 ]
Yoneda, Tatsuo [3 ]
Yoshida, Katsunori [3 ]
Kimura, Hiroshi [2 ]
Mikasa, Keiichi [1 ]
机构：
[1] Nara Med Univ, Ctr Infect Dis, Kashihara, Nara 634, Japan
[2] Nara Med Univ, Dept Internal Med 2, Kashihara, Nara 634, Japan
[3] Nara Med Univ, Dept Urol, Kashihara, Nara 634, Japan
来源：
JOURNAL OF INFECTION AND CHEMOTHERAPY | 2014年 / 20卷 / 1-2期
关键词：
Kidney transplantation; Scedosporium prolificans; Disseminated infection; Infective endocarditis; Meningitis; IN-VITRO ACTIVITIES; POSACONAZOLE PROPHYLAXIS; FUNGAL-INFECTIONS; VORICONAZOLE; PATIENT; OSTEOMYELITIS; LEUKEMIA; THERAPY;
D O I：
10.1016/j.jiac.2013.09.006
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Scedosporium prolificans is a ubiquitous filamentous fungi that may cause disseminated diseases in neutropenic patients with hematological malignancies. We report a fatal case of renal transplant recipient who developed both infective endocarditis and meningitis due to S. prolificans during treatment with micafungin and itraconazole for chronic necrotizing aspergillosis. Breakthrough Scedosporium infection should be considered among differential diagnosis of invasive fungal diseases in patients with renal transplant recipients receiving antifungal agents. (C) 2013, Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码：131 / 133
页数：3
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