Hepatocyte nuclear factor 4 alpha (HNF4α) knockdown stimulates pro-mitogenic gene expression in hepatocytes

被引：0
|
作者：
Walesky, Chad Michael [1 ]
Gunewardena, Sumedha [1 ]
Terwilliger, Ernest F. [2 ]
Edwards, Genea [1 ]
Wolfe, Andy [1 ]
Apte, Udayan [1 ]
机构：
[1] Univ Kansas, Med Ctr, Kansas City, KS 66103 USA
[2] Beth Israel Deaconess Med Ctr, Boston, MA 02215 USA
来源：
FASEB JOURNAL | 2011年 / 25卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Mutations in hepatocyte nuclear factor 4α (HNF4α) gene associated with diabetes result in greater loss of HNF4α function in pancreatic β-cells than in nonpancreatic β-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells
    Bénédicte Oxombre
    Ericka Moerman
    Jerôme Eeckhoute
    Pierre Formstecher
    Bernard Laine
    Journal of Molecular Medicine, 2002, 80 : 423 - 430
  • [42] Mutations in hepatocyte nuclear factor 4α (HNF4α) gene associated with diabetes result in greater loss of HNF4α function in pancreatic β-cells than in nonpancreatic β-cells and in reduced activation of the apolipoprotein CIII promoter in hepatic cells
    Oxombre, W
    Moerman, E
    Eeckhoute, J
    Formstecher, P
    Laine, B
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2002, 80 (07): : 423 - 430
  • [43] Complex Interplay between the Lipin 1 and the Hepatocyte Nuclear Factor 4 α (HNF4α) Pathways to Regulate Liver Lipid Metabolism
    Chen, Zhouji
    Gropler, Matthew C.
    Mitra, Mayurranjan S.
    Finck, Brian N.
    PLOS ONE, 2012, 7 (12):
  • [44] Regulation of human sterol 27-hydroxylase gene (CYP27A1) by bile acids and hepatocyte nuclear factor 4α (HNF4α)
    Chen, WL
    Chiang, JYL
    GENE, 2003, 313 : 71 - 82
  • [45] Hepatocyte Nuclear Factor 4-α (HNF4α) controls the insulin resistance-induced pancreatic β-cell mass expansion
    Barth, Robson
    Ruoso, Carolina
    Ferreira, Sandra Mara
    de Ramos, Francieli Caroline
    Lima, Fernanda Barbosa
    Boschero, Antonio Carlos
    dos Santos, Gustavo Jorge
    LIFE SCIENCES, 2022, 289
  • [46] Mechanical Compaction Accelerates Hepatocyte Repolarization by Directly Activating HNF4α Expression
    Yang, Jinlian
    Liang, Jiaen
    Wang, Yan
    HEPATOLOGY, 2016, 64 : 166A - 166A
  • [47] HNF4 beta, a new gene of the HNF4 family with distinct activation and expression profiles in oogenesis and embryogenesis of Xenopus laevis
    Holewa, B
    Zapp, D
    Drewes, T
    Senkel, S
    Ryffel, GU
    MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (02) : 687 - 694
  • [48] Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences
    Ryffel, GU
    JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2001, 27 (01) : 11 - 29
  • [49] Hepatocyte nuclear factor (HNF)-4α-driven epigenetic silencing of the human PED gene
    P. Ungaro
    R. Teperino
    P. Mirra
    M. Longo
    M. Ciccarelli
    G. A. Raciti
    C. Nigro
    C. Miele
    P. Formisano
    F. Beguinot
    Diabetologia, 2010, 53 : 1482 - 1492
  • [50] Hepatocyte nuclear factor (HNF)-4α-driven epigenetic silencing of the human PED gene
    Ungaro, P.
    Teperino, R.
    Mirra, P.
    Longo, M.
    Ciccarelli, M.
    Raciti, G. A.
    Nigro, C.
    Miele, C.
    Formisano, P.
    Beguinot, F.
    DIABETOLOGIA, 2010, 53 (07) : 1482 - 1492
12345