GDC-0077 is a selective PI3Kalpha inhibitor that demonstrates robust efficacy in PIK3CA mutant breast cancer models as a single agent and in combination with standard of care therapies

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作者
Hong, Rebecca [1 ]
Edgar, Kyle [1 ]
Song, Kyung [1 ]
Steven, Schmidt [1 ]
Young, Amy [1 ]
Hamilton, Patricia [1 ]
Arrazate, Alfonso [1 ]
De La Cruz, Cecile [1 ]
Chan, Connie [1 ]
Pang, Jodie [1 ]
Salphati, Laurent [1 ]
Belvin, Marcia [1 ]
Nannini, Michelle [1 ]
Staben, Steven [1 ]
Friedman, Lori [1 ]
Sampath, Deepak [1 ]
机构
[1] Genentech Inc, San Francisco, CA USA
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R73 [肿瘤学];
学科分类号
100214 ;
摘要
PD4-14
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