BB-UVA vs. NB-UVB in the treatment of vitiligo: a randomized controlled clinical study (single blinded)

被引：14
|
作者：
El-Mofty, Medhat [1 ]
Mostafa, Wedad [1 ]
Youssef, Randa [1 ]
El-Fangary, Mona [2 ]
El-Ramly, Amany [1 ]
Mahgoub, Doaa [1 ]
Fawzy, Marwa [1 ]
El-Hawary, Marwa [1 ]
机构：
[1] Cairo Univ, Phototherapy Unit Kasr El Aini, Fac Med, Cairo, Egypt
[2] Misr Univ Sci & Technol, Dept Dermatol, Fac Med, 6th Of October City, Giza, Egypt
来源：
PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE | 2013年 / 29卷 / 05期
关键词：
BB-UVA; NB-UVA; vitiligo; NARROW-BAND UVB; SKIN; PHOTOTHERAPY; SYSTEM; CELLS; LIGHT; NM;
D O I：
10.1111/phpp.12061
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Background Vitiligo is an acquired pigmentary disorder that affects between 1% and 2% of the general population. Phototherapy remains the cornerstone of treatment, with NB-UVB being the most frequently used. BB-UVA can be a plausible alternative for darker population; skin photo type III and IV. Patients and Methods The study was a prospective, randomized, controlled, and single-blinded clinical trial, conducted on 40 patients with bilateral symmetrical vitiligo. The patients were randomly divided into two equal groups; group (A) received a fixed dose of 15 J/cm2 BB-UVA, while group (B) received NB-UVB. The study was conducted for a period of 16 weeks (48 sessions). Results The final percentage of clinical improvement was significantly higher (P = 0.047) within the BB-UVA group (63.82% +/- 27.42), than within the NB-UVB group (44.32% +/- 29.78). Conclusion BB-UVA can be considered as an alternative treatment line for vitiligo.
引用
收藏
页码：239 / 246
页数：8
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