Successful Induction of Immune Tolerance to Canine Factor VIII after Lentiviral-Mediated Gene Therapy in Neonatal Hemophilia A Mice

被引:0
|
作者
Matsui, Hideto [1 ]
Shibata, Masaru [1 ,2 ]
Brown, Brian [1 ]
Labelle, Andrea [1 ]
Hegadorn, Carol [1 ]
Andrews, Chandler [1 ]
Chuah, Marinee [3 ]
VandenDriessche, Thierry [3 ]
Miao, Carol H. [4 ]
Hough, Christine [1 ]
Lillicrap, David [1 ]
机构
[1] Queens Univ, Dept Pathol & Mol Med, Kingston, ON, Canada
[2] Nara Med Univ, Dept Pediat, Kashihara, Nara, Japan
[3] Univ Louvain, Flanders Interuniv Inst Biotechnol, Ctr Transgene Technol & Gene Therapy, Louvain, Belgium
[4] Univ Washington, Dept Pediat, Seattle, WA 98195 USA
关键词
D O I
10.1016/j.ymthe.2006.08.1193
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
1091
引用
收藏
页码:S419 / S419
页数:1
相关论文
共 50 条
  • [41] OBSERVATIONAL IMMUNE TOLERANCE INDUCTION STUDY (OBSITI): IMMUNE TOLERANCE INDUCTION WITH A SINGLE FACTOR VIII/VON WILLEBRAND FACTOR CONCENTRATE FOR TREATMENT OF HEMOPHILIA A PATIENTS WITH INHIBITORS
    Escuriola-Ettinghausen, C.
    HAEMATOLOGICA, 2019, 104 : 13 - 14
  • [42] Longitudinal profiling of anti-factor VIII antibodies in Japanese patients with congenital hemophilia A during factor VIII replacement and immune-tolerance induction therapy
    Takuji Yoshimura
    Shoko Furukawa
    Akihisa Oda
    Tomoko Matsumoto
    Kana Sasai
    Midori Shima
    Keiji Nogami
    International Journal of Hematology, 2022, 116 : 423 - 433
  • [43] Longitudinal profiling of anti-factor VIII antibodies in Japanese patients with congenital hemophilia A during factor VIII replacement and immune-tolerance induction therapy
    Yoshimura, Takuji
    Furukawa, Shoko
    Oda, Akihisa
    Matsumoto, Tomoko
    Sasai, Kana
    Shima, Midori
    Nogami, Keiji
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022, 116 (03) : 423 - 433
  • [44] Successful induction of immune tolerance to enzyme replacement therapy in canine mucopolysaccharidosis I
    Kakkis, E
    Lester, T
    Yang, R
    Tanaka, C
    Anand, V
    Lemontt, J
    Peinovich, M
    Passage, M
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (03) : 829 - 834
  • [45] Pharmacokinetic analysis identifies a factor VIII immunogenicity threshold after AAV gene therapy in hemophilia A mice
    Lundgren, Taran S.
    Denning, Gabriela
    Stowell, Sean R.
    Spencer, H. Trent
    Doering, Christopher B.
    BLOOD ADVANCES, 2022, 6 (08) : 2628 - 2645
  • [46] Successful use of very high purity factor VIII concentrates in an immune tolerance induction regimen in hemophilia A subjects with high responding inhibitors
    Rocino, A
    Papa, ML
    Salerno, E
    de Biasi, R
    THROMBOSIS RESEARCH, 1998, 91 (03) : S96 - S96
  • [47] Effect of B-Cell Depletion On Inhibitor Antibody Formation and Immune Tolerance Induction to Human Factor VIII in Hemophilia A Mice
    Zhang, Ai-Hong Allan
    Skupsky, Jonathan
    Scott, David W.
    BLOOD, 2009, 114 (22) : 841 - 841
  • [48] Anti-CD3 antibodies modulate anti-factor VIII immune responses in hemophilia Amice after factor VIII plasmid-mediated gene therapy
    Peng, Baowei
    Ye, Peiqing
    Rawlings, David J.
    Ochs, Hans D.
    Miao, Carol H.
    BLOOD, 2009, 114 (20) : 4373 - 4382
  • [49] Novel Strategies To Modulate Pre-Existing Anti-Factor VIII Immune Responses in Hemophilia A Inhibitor Mice Treated with Factor VIII Plasmid-Mediated Gene Therapy
    Liu, ChaoLien
    Ye, Peiqing
    Lin, Jacqueline
    Miao, Carol H.
    MOLECULAR THERAPY, 2012, 20 : S275 - S276
  • [50] Immune Tolerance Induction in Severe Hemophilia a Patients Using Wilate, a Von Willebrand Factor/Factor VIII Concentrate
    Wu, John K.
    Woo, Celina
    Crilly, Erica
    BLOOD, 2014, 124 (21)