Drug-Associated Thrombotic Microangiopathies

被引：18
|
作者：
Kreuter, Justin [1 ]
Winters, Jeffrey L. [1 ,2 ]
机构：
[1] Mayo Clin, Dept Lab Med & Pathol, Div Transfus Med, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Lab Med & Pathol, Therapeut Apheresis Treatment Unit, Rochester, MN 55905 USA
来源：
SEMINARS IN THROMBOSIS AND HEMOSTASIS | 2012年 / 38卷 / 08期
关键词：
drug; thrombotic microangiopathy; plasma exchange; HEMOLYTIC-UREMIC SYNDROME; ENDOTHELIAL GROWTH-FACTOR; INDUCED IMMUNE THROMBOCYTOPENIA; RENAL-CELL CARCINOMA; PLASMA-EXCHANGE; CYCLOSPORINE-A; MITOMYCIN-C; FACTOR VEGF; PURPURA; TICLOPIDINE;
D O I：
10.1055/s-0032-1328886
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Thrombotic microangiopathy is a pathological process that results in thrombocytopenia, schistocytes, and organ ischemia. A wide variety of causes of thrombotic microangiopathy have been described, each associated with a different pathological stimulus and predisposition toward certain vascular territories. This review will summarize our understanding of key drugs that have been classically and newly associated with thrombotic microangiopathy as well as mention of treatment options focusing on the role of plasma exchange.
引用
收藏
页码：839 / 844
页数：6
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