Correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus

被引:323
|
作者
Cui, LZ
Tominaga, E
Neoh, HM
Hiramatsu, K
机构
[1] Juntendo Univ, Fac Med, Dept Bacteriol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Juntendo Univ, Fac Med, Dept Infect Control Sci, Bunkyo Ku, Tokyo 1138421, Japan
关键词
D O I
10.1128/AAC.50.3.1079-1082.2006
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We present here findings of a strong positive correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus (VISA). This correlation is related to cell wall thickening, suggesting that, similar to the case with vancomycin resistance in VISA, the physical barrier of a thickened cell wall may contribute to daptomycin resistance in S. aureus.
引用
收藏
页码:1079 / 1082
页数:4
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